ID A0A0R1UGU2_9LACO Unreviewed; 444 AA.
AC A0A0R1UGU2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700};
GN ORFNames=FC21_GL000216 {ECO:0000313|EMBL:KRL92623.1};
OS Limosilactobacillus equigenerosi DSM 18793 = JCM 14505.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Limosilactobacillus.
OX NCBI_TaxID=1423742 {ECO:0000313|EMBL:KRL92623.1, ECO:0000313|Proteomes:UP000051084};
RN [1] {ECO:0000313|EMBL:KRL92623.1, ECO:0000313|Proteomes:UP000051084}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18793 {ECO:0000313|EMBL:KRL92623.1,
RC ECO:0000313|Proteomes:UP000051084};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|PIRNR:PIRNR005700}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL92623.1}.
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DR EMBL; AZGC01000053; KRL92623.1; -; Genomic_DNA.
DR RefSeq; WP_056995779.1; NZ_AZGC01000053.1.
DR AlphaFoldDB; A0A0R1UGU2; -.
DR STRING; 417373.GCA_001570685_01131; -.
DR PATRIC; fig|1423742.4.peg.228; -.
DR OrthoDB; 1111399at2; -.
DR Proteomes; UP000051084; Unassembled WGS sequence.
DR GO; GO:0070005; F:cysteine-type aminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00585; Peptidase_C1B; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR004134; Peptidase_C1B.
DR PANTHER; PTHR10363; BLEOMYCIN HYDROLASE; 1.
DR PANTHER; PTHR10363:SF2; BLEOMYCIN HYDROLASE; 1.
DR Pfam; PF03051; Peptidase_C1_2; 1.
DR PIRSF; PIRSF005700; PepC; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|PIRNR:PIRNR005700,
KW ECO:0000313|EMBL:KRL92623.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR005700};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PIRNR:PIRNR005700};
KW Reference proteome {ECO:0000313|Proteomes:UP000051084};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807,
KW ECO:0000256|PIRNR:PIRNR005700}.
FT ACT_SITE 70
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 365
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
FT ACT_SITE 386
FT /evidence="ECO:0000256|PIRSR:PIRSR005700-1"
SQ SEQUENCE 444 AA; 50612 MW; 9AA0F017AC27AD83 CRC64;
MSFAISPADL ASFSADYQAD QTNAVLERAV TKNGVQAASF DWHAKADNDQ HFSIDLKTGK
VANQKQSGRC WMFAALNTMR HDMQQKFNLP TDFELSQSYQ FFWDKFEKAN YFYENVVKTA
ELPTDDRKVA WLMETPQQDG GQWDMLVALI DKYGVVPQSA MPESYNSSRS NELNAVLNQK
LRHDAVILRQ AIADGETETQ INARRKAMMN DVYRMLAYAF GEPVQEFTFE YRDEAGEFHR
EAGLTPKTFF AKYVGWNLDD YVSIINAPTQ DKEYHQTYTI EMLGNVVGGR QVKHLNLPMA
EFKQLAVDQL KAGESVWFGA DVSQMSERKM GILALNTFGY EDLFKTQLTM SKEDALDYSQ
SMMNHAMVLT GVDLVDDQPT KWKVENSWGE QVGEKGYFVM SDAWMDKFCY QVVVNKKYLS
DELKAAQAAE PVVLKPWDPM GTLA
//
