ID A0A0R1UHE7_9LACO Unreviewed; 416 AA.
AC A0A0R1UHE7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Xanthine permease {ECO:0000313|EMBL:KRL90245.1};
GN ORFNames=FC46_GL000256 {ECO:0000313|EMBL:KRL90245.1};
OS Lactobacillus kalixensis DSM 16043.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1423763 {ECO:0000313|EMBL:KRL90245.1, ECO:0000313|Proteomes:UP000051036};
RN [1] {ECO:0000313|EMBL:KRL90245.1, ECO:0000313|Proteomes:UP000051036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16043 {ECO:0000313|EMBL:KRL90245.1,
RC ECO:0000313|Proteomes:UP000051036};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRL90245.1}.
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DR EMBL; AZFM01000012; KRL90245.1; -; Genomic_DNA.
DR RefSeq; WP_057798402.1; NZ_AZFM01000012.1.
DR AlphaFoldDB; A0A0R1UHE7; -.
DR STRING; 1423763.FC46_GL000256; -.
DR PATRIC; fig|1423763.3.peg.261; -.
DR OrthoDB; 9805749at2; -.
DR Proteomes; UP000051036; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR017588; UacT-like.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR NCBIfam; TIGR03173; pbuX; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 416 AA; 44602 MW; F78DBE2441656303 CRC64;
MQKEVNHKKA AVLGLQHLLA MYSGAIAVPL LIGNALHFNS THMTYLVSID IFMCGLATLI
QLFRNKYFGI GLPVVLGCAI QAVAPLEMIG QKFSINTMYG AIIVAGIFVF CIAGWFSKVK
KLFPPVVTGT LITVIGLTLI PVAVQNMGGG NASAKNFGDP KNLVLSFVTV LIILLVEILA
KGFLRSISVL IGLVAGTLLA SAMGMVSLEP VKQAAWFHLP QIFYFGVPEF EWSSSLTMII
IALVSMVEST GVFFAIGDLL NKDITEDDLK RGYRAEGLAQ IFGGIFNTFP YTTFSQNVGL
LQLSGIKTKR PIFWAASLLM AMGLLPKIGG LVTIIPDPVL GGAMLVMFTM IAVQGIKMLV
KVDFNDNRNM LIIAISIGLG LGVTVYPQIF QALPQAVQLF LGNGIVVASV SATLLN
//
