ID A0A0R1VWM4_9LACO Unreviewed; 730 AA.
AC A0A0R1VWM4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=ATP-dependent Clp protease {ECO:0000313|EMBL:KRM09797.1};
GN ORFNames=FD16_GL001555 {ECO:0000313|EMBL:KRM09797.1};
OS Paucilactobacillus suebicus DSM 5007 = KCTC 3549.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Paucilactobacillus.
OX NCBI_TaxID=1423807 {ECO:0000313|EMBL:KRM09797.1, ECO:0000313|Proteomes:UP000051820};
RN [1] {ECO:0000313|EMBL:KRM09797.1, ECO:0000313|Proteomes:UP000051820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5007 {ECO:0000313|EMBL:KRM09797.1,
RC ECO:0000313|Proteomes:UP000051820};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM09797.1}.
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DR EMBL; AZGF01000035; KRM09797.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R1VWM4; -.
DR STRING; 1423807.FD16_GL001555; -.
DR PATRIC; fig|1423807.3.peg.1594; -.
DR eggNOG; COG0542; Bacteria.
DR Proteomes; UP000051820; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:KRM09797.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:KRM09797.1}.
FT DOMAIN 335..370
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT REGION 50..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 357..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 51..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 80075 MW; 242C0B6EBFC39A52 CRC64;
MNGQEVQVDL CQNCYQMMKD AQNNLMNGGN GMAQNPFGFG NLDDLLKAMQ GQGGAQQQSG
QQAFNGQTQA QGGQGGNNGG NSLLAQFGVN MTDLAKQGKI DPVIGRDKEI ARVIEILNRR
TKNNPVLIGE AGVGKTAVVE GLAQAIVSGQ VPQKLNNKEI IRLDVVSLVQ GTGIRGQFEQ
RMQQLMKEVS KNKNVILFID EIHEIMGAGN AEGGMDAGNV LKPALARGDF QLIGATTLSE
YRKIEKDSAL ARRFQQIQVD EPSVQETIQI LNGIKNRYQD YHNVKYTDES IDAAAKLSAR
YIQDRFLPDK AIDLLDEAGS KKNLTLKTAD PATIENEIHT AEAHKQQALD NEDYEKAAFY
RDQVAKLEKA KKDAEENHTD TAATVTVEDM QKIVEEKTNI PVGDLAKQEE NQLKDLNKNL
SAHVIGQDEA VDKVSRAIRR NRIGLNKSGR PIGSFLFVGP TGVGKTETAK QLAKELFGSE
DSMIRFDMSE YMEKHSTSKL IGSPPGYVGY EEAGQLTEQV RRHPYSLILL DEIEKAHPDV
MHMFLQILDD GRLTDSQGRT VSFKDTIIIM TSNAGSGDSE ASVGFGAEAS GSTHSILDKL
GNYFKPEFLN RFDAIVEFNA LTKDNLMKIV SLMTDDVNKM LADRGLFINV TDPVKSKLVD
LGFDPTMGAR PLRRVIQEQI EDRIADFVLD NPKTKNLEAV LDNDKIVVTG ASLPNPGTVT
TDASTSDTDK
//
