ID A0A0R1XCH0_9LACO Unreviewed; 603 AA.
AC A0A0R1XCH0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN ORFNames=FC91_GL002310 {ECO:0000313|EMBL:KRM27847.1};
OS Schleiferilactobacillus harbinensis DSM 16991.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Schleiferilactobacillus.
OX NCBI_TaxID=1122147 {ECO:0000313|EMBL:KRM27847.1, ECO:0000313|Proteomes:UP000050949};
RN [1] {ECO:0000313|EMBL:KRM27847.1, ECO:0000313|Proteomes:UP000050949}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16991 {ECO:0000313|EMBL:KRM27847.1,
RC ECO:0000313|Proteomes:UP000050949};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM27847.1}.
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DR EMBL; AZFW01000040; KRM27847.1; -; Genomic_DNA.
DR RefSeq; WP_027828142.1; NZ_AZFW01000040.1.
DR AlphaFoldDB; A0A0R1XCH0; -.
DR PATRIC; fig|1122147.4.peg.2389; -.
DR eggNOG; COG3250; Bacteria.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000050949; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154};
KW Reference proteome {ECO:0000313|Proteomes:UP000050949}.
FT DOMAIN 17..183
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 198..276
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 279..595
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 603 AA; 68608 MW; 9640445C4156F23E CRC64;
MEQSLLYPVV NAVRTDQKLD GLWRFSFDAV GVGPQEGWAK HLPKAVDMPV PASFNDFFTD
KDAREYTGDF WYEKKFFVPA DYQGRFVGLR FDAVTHRATI YVNGVKIRSH EGGFLPFVAD
VTDALHYGEE NTVVVQGNNE LSREALPAGD TITLKNGKKM ARPFFDFYNY SGINRSVHLI
TLPVERITDY TTDFTLAGAD ADVHYTVTTT GDHDVVAVLR DADGQVVAEN IGKQGTLHVT
DAHLWNVRAA YLYTLTLQIT NDTTIVDEYS AEIGIRTIKI VGTEIQVNGK SVYLKGFGRH
EDSPFAGRAF DLNVEKKDFS LMQWSGANSF RTSHYPYDEQ VYQMADREGF LVIDEVPAVG
FKMVAASFLG GLNQSFFKGP WIKPLHAKHL DQITDMIKRD KNHPSVFAWS LLNEPDTVTE
ESVPYFKQIF AETKDLDPQS RPRTFSLSED DTIETSKDLD FPDIYLLNRY PGWYHYAGYQ
ILDGEAGLRE EMDKWAASGI NKPIVFTEFG ADTEAGLHKL PSVMWSEEYQ VEVLEMFSRI
FDSYPFIKGE QVWNFADFQT VEGNMRVNGN KKGIFTRDRQ PKAAAFFYHK RWTNIPLDYK
AQK
//
