ID A0A0R1XIY2_9LACO Unreviewed; 254 AA.
AC A0A0R1XIY2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Oxygen-insensitive nadph nitroreductase {ECO:0000313|EMBL:KRM30119.1};
GN ORFNames=FC91_GL002933 {ECO:0000313|EMBL:KRM30119.1};
OS Schleiferilactobacillus harbinensis DSM 16991.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Schleiferilactobacillus.
OX NCBI_TaxID=1122147 {ECO:0000313|EMBL:KRM30119.1, ECO:0000313|Proteomes:UP000050949};
RN [1] {ECO:0000313|EMBL:KRM30119.1, ECO:0000313|Proteomes:UP000050949}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16991 {ECO:0000313|EMBL:KRM30119.1,
RC ECO:0000313|Proteomes:UP000050949};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the flavin oxidoreductase frp family.
CC {ECO:0000256|ARBA:ARBA00008366, ECO:0000256|PIRNR:PIRNR005426}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM30119.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZFW01000006; KRM30119.1; -; Genomic_DNA.
DR RefSeq; WP_027828758.1; NZ_AZFW01000006.1.
DR AlphaFoldDB; A0A0R1XIY2; -.
DR PATRIC; fig|1122147.4.peg.3019; -.
DR eggNOG; COG0778; Bacteria.
DR OrthoDB; 9775805at2; -.
DR Proteomes; UP000050949; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR InterPro; IPR016446; Flavin_OxRdtase_Frp.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR PANTHER; PTHR43425; OXYGEN-INSENSITIVE NADPH NITROREDUCTASE; 1.
DR PANTHER; PTHR43425:SF2; OXYGEN-INSENSITIVE NADPH NITROREDUCTASE; 1.
DR Pfam; PF00881; Nitroreductase; 1.
DR PIRSF; PIRSF005426; Frp; 1.
DR SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
PE 3: Inferred from homology;
KW Flavoprotein {ECO:0000256|PIRNR:PIRNR005426};
KW FMN {ECO:0000256|PIRNR:PIRNR005426}; NADP {ECO:0000256|PIRNR:PIRNR005426};
KW Oxidoreductase {ECO:0000256|PIRNR:PIRNR005426};
KW Reference proteome {ECO:0000313|Proteomes:UP000050949}.
FT DOMAIN 15..166
FT /note="Nitroreductase"
FT /evidence="ECO:0000259|Pfam:PF00881"
SQ SEQUENCE 254 AA; 28186 MW; A7FA08596DC6A42E CRC64;
MADQTHSFID TLLHHTSIRA FQDTAVPAET LRTLEDVAQH TASSQYMQQF TLIRVTEPDL
RQKIAALTTH QYIAGPGTFY VFVVDQARNV RLADNLHAAT TRLTDWNAFL AGVFDATLAA
QNMVAAAEST GLGTVYLGSI LNDPQQMIDL LHLPRYTFPL LGLMVGVPAD KPDAKPRLPH
ALVVGRNGYP QPADTPALWD TYNQAVHTYY ADRSSQPRDT DFARMVVANS QGDPHHRGEI
GRILKRQGFQ LPQK
//
