ID A0A0R1ZE75_9LACO Unreviewed; 224 AA.
AC A0A0R1ZE75;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=NADPH-flavin oxidoreductase {ECO:0000313|EMBL:KRM53184.1};
GN ORFNames=FC64_GL000846 {ECO:0000313|EMBL:KRM53184.1};
OS Ligilactobacillus araffinosus DSM 20653.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1423820 {ECO:0000313|EMBL:KRM53184.1, ECO:0000313|Proteomes:UP000051291};
RN [1] {ECO:0000313|EMBL:KRM53184.1, ECO:0000313|Proteomes:UP000051291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20653 {ECO:0000313|EMBL:KRM53184.1,
RC ECO:0000313|Proteomes:UP000051291};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- SIMILARITY: Belongs to the nitroreductase family.
CC {ECO:0000256|ARBA:ARBA00007118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM53184.1}.
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DR EMBL; AYYZ01000006; KRM53184.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R1ZE75; -.
DR STRING; 1423820.FC64_GL000846; -.
DR PATRIC; fig|1423820.4.peg.867; -.
DR Proteomes; UP000051291; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd02149; NfsB-like; 1.
DR Gene3D; 3.40.109.10; NADH Oxidase; 1.
DR InterPro; IPR033878; NfsB-like.
DR InterPro; IPR029479; Nitroreductase.
DR InterPro; IPR000415; Nitroreductase-like.
DR PANTHER; PTHR23026; NADPH NITROREDUCTASE; 1.
DR PANTHER; PTHR23026:SF125; OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE; 1.
DR Pfam; PF00881; Nitroreductase; 1.
DR SUPFAM; SSF55469; FMN-dependent nitroreductase-like; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000051291}.
FT DOMAIN 19..182
FT /note="Nitroreductase"
FT /evidence="ECO:0000259|Pfam:PF00881"
SQ SEQUENCE 224 AA; 25814 MW; F1635BE49DD325E4 CRC64;
MIIMSTQEER QHIIDVFHRR YATKKFNLNK KISDPDWQTI IEAGRLSPSS FGYEPWKFLL
IENPKIKEDL KKICWGAVNS LNGASHFVII LARKNVTITS PHVEHMVEDV MGVNFDIHSP
RSEKFKSFQE NDFDLNNDRA LFDWASKQTY IPLTNMMTVA AELGIDICPI EGFNRAKVDK
YLADKGIIDP DKFGVSVMLG LGYRDQEQPK KTRQPLEEVL EVIK
//
