ID A0A0R1ZM61_9LACO Unreviewed; 1410 AA.
AC A0A0R1ZM61;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Transport protein {ECO:0000313|EMBL:KRM51852.1};
GN ORFNames=FC64_GL001045 {ECO:0000313|EMBL:KRM51852.1};
OS Ligilactobacillus araffinosus DSM 20653.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1423820 {ECO:0000313|EMBL:KRM51852.1, ECO:0000313|Proteomes:UP000051291};
RN [1] {ECO:0000313|EMBL:KRM51852.1, ECO:0000313|Proteomes:UP000051291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20653 {ECO:0000313|EMBL:KRM51852.1,
RC ECO:0000313|Proteomes:UP000051291};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM51852.1}.
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DR EMBL; AYYZ01000029; KRM51852.1; -; Genomic_DNA.
DR RefSeq; WP_057906895.1; NZ_AYYZ01000029.1.
DR STRING; 1423820.FC64_GL001045; -.
DR PATRIC; fig|1423820.4.peg.1069; -.
DR Proteomes; UP000051291; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR InterPro; IPR023908; xxxLxxG_rpt.
DR NCBIfam; TIGR03057; xxxLxxG_by_4; 5.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051291};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1236..1255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1262..1282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1294..1315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1336..1359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1365..1398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1267..1394
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT COILED 719..778
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 809..905
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1410 AA; 148637 MW; 60EA0F16D0DFEB23 CRC64;
MKQKDGSKKR YIVQAIIWII LLIASLITLP NINQLVREKG QIKLPSDLTS QVADNIQNHW
GRHEDNTRQV VVVFNNGDRK LSANQQDNID ATINSFKHQE NKYHIKSMTA PNENKYTRAQ
LISKDKTTEI LQLNVDKKIT VAKTRELITK GAKTPGVKTY VTGSDILNDD FISETQEGIK
KTETITIVFI FIVLALIFRS PLTPIFSLLS VGISMLISLS VVMNLAKHFN FPLSNFTQVF
MVVVLFGIGT DYNILMFDQF KEELSKGLSP LQATRRSLRI AGKTILFSGS SVLIGFSTLG
LAKFSIYRSA VGVAVSVAIL LLALLTLNPF FMAMLGKKIF WPSKKFNGSS TNKMWHNISK
TMVKMPFIGL IVTALCALPF LLSKGSPLNY DTLVELNDSV PAKQGFKVVQ KHFSKGTAEP
TTLYIKTDHP VDNEKDLKEI DELARQIQAV KGVKTVATVT EPGGSKLKEL YVNDQLKTVT
NGTKDARKGL NQISDGLDGA NFQLKGANIQ TGVDGAKKLY DGSQQLQAGA NTLANGASTL
GNGMVTYANG VYTLNNGMSQ LAAATGGLGS GVDALYNGAN ALNSGLATLN SKTSTLSTGV
NALFNGANAL NGGLSTLNSK TGALSTGVNA LFNGANALNG GLSTLNSKTG ALSTGVNKLT
DGSNQLVNGS NELADKLNAA KNNQQLAQLG PKVKELQTGA NQVADGLKQV QNQLNSSQMQ
QLKSQLGNLT NALSQLQNAA TPDISGIQKT AQALSSNSDK AKTDAGNLQN ALNQLKQAAG
SASSGSAGLS NQDINNIVNS VQGLNDSQKQ QLQGALQSAS NQIMQKQQQM MSGLSNSINN
ATNSAQALQN DMQSVSSSGS DLSNQLNQLQ STAEQLSKLK TMASQSQTQE AVNNLNNAVN
QLQGAINKLA PGSSQVADGV GQLSQATGQI QDMVNQAAAG ATQISNGANA LNGGLNQLGS
QVPALTSGIA QLANGSNQLA GGIGSMKGQL PTLTGGIAQL ANGSNQLAGG IGSMKNQLPA
LTGGVAQLAN GSNQLAGGIG SMRSQMPTML GAISALSAGT GELAANAPAL VSGAGQVSSG
AALLAQNQGT LTNGLGQMYS QINGMAGQVN ELETGLTTAS NGAKKINSGL GTANSYLTGL
KDSAAADTYY VPKDVLRSKE YKKAEDSYLS QNKHAVKFTI VLNENPSSLS AMKTVENIQS
LVNKSIKGTS LSGAKVALGG QTAYINDTRN VASKDFIRTA IIMLTGILLA LMLITRSILQ
PFYILGTLLL AYIMSLDITH LISKAFLGQS MLTWNTPFFS FIMLIALGVD YSIFLMMKYQ
EYDGFLATPG ARIVKAATEI GAVVVSAALI LSGTFAALMP SGVLTLIQVA LVVIIGLTIL
VFAIPTIIPS LLSLTYPIKD KMDKKTKKKH
//
