ID A0A0R2AHE1_9LACO Unreviewed; 938 AA.
AC A0A0R2AHE1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Ntrc family transcriptional regulator {ECO:0000313|EMBL:KRM66464.1};
GN ORFNames=FC14_GL001967 {ECO:0000313|EMBL:KRM66464.1};
OS Ligilactobacillus agilis DSM 20509.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1423718 {ECO:0000313|EMBL:KRM66464.1, ECO:0000313|Proteomes:UP000051008};
RN [1] {ECO:0000313|EMBL:KRM66464.1, ECO:0000313|Proteomes:UP000051008}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20509 {ECO:0000313|EMBL:KRM66464.1,
RC ECO:0000313|Proteomes:UP000051008};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM66464.1}.
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DR EMBL; AYYP01000001; KRM66464.1; -; Genomic_DNA.
DR RefSeq; WP_056975515.1; NZ_AYYP01000001.1.
DR AlphaFoldDB; A0A0R2AHE1; -.
DR PATRIC; fig|1423718.3.peg.2041; -.
DR OrthoDB; 9771372at2; -.
DR Proteomes; UP000051008; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00006; PTS_IIA_man; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.510; Phosphotransferase system, mannose-type IIA component; 1.
DR Gene3D; 1.10.1790.10; PRD domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR004701; PTS_EIIA_man-typ.
DR InterPro; IPR036662; PTS_EIIA_man-typ_sf.
DR InterPro; IPR033887; PTS_IIA_man.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071:SF90; TRANSCRIPTIONAL REGULATORY PROTEIN LEVR; 1.
DR Pfam; PF03610; EIIA-man; 1.
DR Pfam; PF00874; PRD; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53062; PTS system fructose IIA component-like; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 2.
DR PROSITE; PS51372; PRD_2; 2.
DR PROSITE; PS51096; PTS_EIIA_TYPE_4; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000051008};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 126..360
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT DOMAIN 476..581
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 582..718
FT /note="PTS EIIA type-4"
FT /evidence="ECO:0000259|PROSITE:PS51096"
FT DOMAIN 839..938
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
SQ SEQUENCE 938 AA; 105125 MW; 5EC1E56EEFADD310 CRC64;
MKRIDKVYQG LVTKWQAATK EEVLAKQGSA AKELAAELGL TRANTSLELN KLVRQAQVVK
IKTFPVRYLP MIVIEQHFGL KQLDYYEVAS LTALTKKPVK PTAKPEQAIK EAASEQVNQA
DPLESMIGYR GSLHNAVSQA KAALMYPPHG LHMMLLGQTG VGKTYFANKI YAYAKFAQIL
KEDAPFVSFN CADYYNNPQL LMATLFGHAK GAYTGADQEK AGLVEQANGG ILLLDEVHRL
PPEGQEMLFY FIDNGVFNRL GESQKKRHAQ VLIICATTEN PDSAMLATFL RRIPMSITIP
ALDERPITER IELAHFLFQT ETKRIKRALS VKRSVFEIIL NEDNYGNVGQ LKSQIQLTCA
QAFLNSMGEK TTISVTDNDL PEKLRQSWLA VSRAERKQSD LSRYLKSQIL IEVGQPSLDK
LDNEENIYST IETKVHKLRA EGINEKEIHQ YIMTDLHLHI KNFFKQEINE ENFSKFVDPA
AIKLAEKLKL IAEEEMDLRF DASFIHYFSL HLDAFFKRGS KNDLLMSAEI ENIKREHGLE
YQVAKLFQTE ILKETGTAIP DIEVIYLTML LTSIESMSAT KKIGLLVVAH GNSTATSMVN
VATELLGKGN IDALDMPLTV SPSTIYEQMK TKVGELNQGK GVLLLVDMGS LGMFTQKLAT
ETGIPVRAVQ NVTTSIILEA LRKVNYIDMD LNSLANQLRR DFIKNFAVQE KSTGKKRAIV
SICMTGSGTA LKLKKLIEGI IRKTTTENIE VKTVSALKMS ESIPPLAKEY ELIATVGTKE
PSVAVPFISL EDLIASNGEA RLEAIIRQQT PPAKEKQSQS NVVVSQMCED ILNEHLVYLN
PRLVNQMLQN WLEDLSRRLK LELSNSQQIA CIVHTAFALE RASHHQTSLN YDETPSPELL
ELLPVVKQTL DHAVSSLKLT LPQDEYYFIA ETVIDNQR
//
