ID A0A0R2AZX2_9LACO Unreviewed; 1158 AA.
AC A0A0R2AZX2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=ATP-dependent nuclease, subunit B {ECO:0000313|EMBL:KRM72679.1};
GN ORFNames=FC34_GL000389 {ECO:0000313|EMBL:KRM72679.1};
OS Lacticaseibacillus brantae DSM 23927.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=1423727 {ECO:0000313|EMBL:KRM72679.1, ECO:0000313|Proteomes:UP000051672};
RN [1] {ECO:0000313|EMBL:KRM72679.1, ECO:0000313|Proteomes:UP000051672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23927 {ECO:0000313|EMBL:KRM72679.1,
RC ECO:0000313|Proteomes:UP000051672};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM72679.1}.
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DR EMBL; AYZQ01000001; KRM72679.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2AZX2; -.
DR STRING; 1423727.FC34_GL000389; -.
DR PATRIC; fig|1423727.3.peg.391; -.
DR Proteomes; UP000051672; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR049035; ADDB_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR PANTHER; PTHR30591; RECBCD ENZYME SUBUNIT RECC; 1.
DR PANTHER; PTHR30591:SF1; RECBCD ENZYME SUBUNIT RECC; 1.
DR Pfam; PF21445; ADDB_N; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000051672}.
FT DOMAIN 8..257
FT /note="ATP-dependent helicase/deoxyribonuclease subunit B
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF21445"
FT DOMAIN 776..1103
FT /note="PD-(D/E)XK endonuclease-like"
FT /evidence="ECO:0000259|Pfam:PF12705"
SQ SEQUENCE 1158 AA; 130251 MW; 1E921C81E520E99B CRC64;
MRRMSLEFII GPASKNHTQL ISAQIKAVLA NDPEAQVFYL VPNHIKFESE VNLLKQLTDD
PISVQTRLQV LSFSRLAWFY LKDLPVYQLP RLNSGNNTLL VAKILQDHKA ELNLYQTEAD
HPGFVVQLAQ QLNELALGRI GGDDLQTLNQ EQGTQNPNPK KFADLSVLLS AYTQALGQFV
TPSSLLDALT EQLNNTDLSH TYFYLNYFNS LNASELHLME CLIKNSAGVT VALTHNQDET
SRLFHQSQRL LEQLRQFDPS AKFVTHLPER QMAPMMAEVE EFWLSVTDQS TQPKPKTTGN
LTVAMASDPY AELRQVAREI VQKVHAGARY RDFLIMARHL DPYTSSIPAI FSEFNLPYFV
DVEHPMANHP LVVLIDTLFE VQRSNYSYAS MMRLLRTELL IPESMPLSDF RAALDVTDNH
LLRTGMTGRY WRQSDPWQYF QRYNDATTEL DSQKSTQINQ IKDWVAQTVT PVLNQLKASE
SSQDAAAVLY QWLLSAGVKA QLNAQRQAAT AAGDLMQAQA IAQVWQTVCD LLDDFVSAFG
QQPYQARQFQ QLLNAGFAGA TFTQIPSTLD QVVISETGLT RLQQAQHVYV IGATSTVMPD
IQTETSILTQ SDRDFLEDRL AQQDRPTDQF LPATGPRTVL DDPFINYLGF MAGNQMLTIS
YPVHNETDLQ PSIYVTQLQA YFGLTPAIWQ SPTSKTTVKL ALGSPRSLLS DGIQVLRLAT
DAQQVLASDW QSLFQTLRQS PLAGLSRHLL SSIDFQNTVG SLSPEIAEAL YGDVIRVSVS
QLETYFKNPF EYFLRYGLRL QKRPEFELSP ADTGTLFHGV LDQFVSQQDL NTVTPATIQT
VVAQLMADFS QQPGFEILQS SARFRFITAQ LQRVLVQTLT AIVQQQKQSD FHPRATELLF
GQIGGQKGLQ PLIYPLPGGK AVQMRGKIDR LDTFSDGQST YFLIVDYKSS DHRFNDSDAY
YGVALQMLTY MDAVRNQTSD QPLIPAGALY FRLYNPRLDY QRDADPSQLA DEMLGQFQMH
GFLVNHDTPD DPILYHLDKT ATPDNPAKSK LVELAYRKDG QLAKHGVNII GVGDLEQLLA
HNRQNIVNAA TQIANGVIDL APFQYDQKAE TITQSDFVAI MQFDPALLSN NYHQVEKLDR
QTVLDKLKEK ADGNEVDE
//
