ID A0A0R2D7P4_9LACO Unreviewed; 326 AA.
AC A0A0R2D7P4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Acetoin dehydrogenase complex {ECO:0000313|EMBL:KRM99889.1};
GN ORFNames=FC24_GL001721 {ECO:0000313|EMBL:KRM99889.1};
OS Loigolactobacillus rennini DSM 20253.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Loigolactobacillus.
OX NCBI_TaxID=1423796 {ECO:0000313|EMBL:KRM99889.1, ECO:0000313|Proteomes:UP000051638};
RN [1] {ECO:0000313|EMBL:KRM99889.1, ECO:0000313|Proteomes:UP000051638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 20253 {ECO:0000313|EMBL:KRM99889.1,
RC ECO:0000313|Proteomes:UP000051638};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRM99889.1}.
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DR EMBL; AYYI01000005; KRM99889.1; -; Genomic_DNA.
DR RefSeq; WP_057872958.1; NZ_AYYI01000005.1.
DR AlphaFoldDB; A0A0R2D7P4; -.
DR STRING; 1423796.FC24_GL001721; -.
DR PATRIC; fig|1423796.3.peg.1749; -.
DR OrthoDB; 9771835at2; -.
DR Proteomes; UP000051638; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000051638}.
FT DOMAIN 4..180
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 326 AA; 35161 MW; 121E1E3A465F3341 CRC64;
MTEHTYLEAL NLAMHEEFAR DPGVVVFGED VGGDKGGVFG ATKGLAAAFG DQRVFNSPLG
ESGIAGLAIG LGLMGHHAIA EFQFADYILP AVNQIMSEAA RMRYRTAGDW TAPIVFRTPY
GGGVHGGFYH SQTTDKVFAG QPGLRIVTPS TVYDAKGLLK AAIRSEDPVL FYEHKRLYRS
LKADIPDEDY VVPLDKAQVL QQGDDITVMA YGTMLQHALN AAKALQAEDI STEVVDLRTL
YPLDQETILA AAKKTGKVLL ISEDTKEASI INNVAAIIAE QALFDLDAPV QQLAGPLAPG
MSYALEDEFL VSAEQVQAAM RELAQF
//
