ID   A0A0R2D9C8_9LACO        Unreviewed;       765 AA.
AC   A0A0R2D9C8;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=DNA helicase superfamily protein I {ECO:0000313|EMBL:KRM97195.1};
GN   ORFNames=FC24_GL001643 {ECO:0000313|EMBL:KRM97195.1};
OS   Loigolactobacillus rennini DSM 20253.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Loigolactobacillus.
OX   NCBI_TaxID=1423796 {ECO:0000313|EMBL:KRM97195.1, ECO:0000313|Proteomes:UP000051638};
RN   [1] {ECO:0000313|EMBL:KRM97195.1, ECO:0000313|Proteomes:UP000051638}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20253 {ECO:0000313|EMBL:KRM97195.1,
RC   ECO:0000313|Proteomes:UP000051638};
RX   PubMed=26415554; DOI=10.1038/ncomms9322;
RA   Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA   Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA   Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA   Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA   de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA   Zhang H., O'Toole P.W.;
RT   "Expanding the biotechnology potential of lactobacilli through comparative
RT   genomics of 213 strains and associated genera.";
RL   Nat. Commun. 6:8322-8322(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRM97195.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AYYI01000044; KRM97195.1; -; Genomic_DNA.
DR   RefSeq; WP_057874187.1; NZ_AYYI01000044.1.
DR   AlphaFoldDB; A0A0R2D9C8; -.
DR   STRING; 1423796.FC24_GL001643; -.
DR   PATRIC; fig|1423796.3.peg.1670; -.
DR   OrthoDB; 9787585at2; -.
DR   Proteomes; UP000051638; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR048228; HelD_bacillota.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   NCBIfam; NF041464; HelD_BACSU; 1.
DR   PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000051638}.
FT   DOMAIN          209..601
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         230..237
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   765 AA;  88897 MW;  58707684C7A34067 CRC64;
     MADTNKQQEQ ARVDDVIRKI KQTESDLKQK ITAAKSDEKQ INNNFYNDVR INVGSYESLM
     DTALSIRQQQ QMLNERNNSW QHSAQHLDVL QRLEKTPYFA RIDFQEDRET KPETIYIGLS
     SFTDQHNHFL IYDWRAPISS IYYDGNLGRV TYQTPDGQQA VDVKLKRQFI IHDGQIQTMF
     DTQETIGDQM LMEVLGEQAD TKMKSIVTTI QREQNQIIRD TKAKLLFVQG AAGSGKTSAI
     MQRVAYLLYR YRGNLNSSQV IMFSPNQLFN DYVGGVLPEL GEQNMVQLTY YQYAARRLPN
     ITVENLFTRF EKAESKLDKR IDQLKGSLAF AQATQQYAHS LEKQGMRFRD IKLRHEVFID
     QARIVKNYYK YNANYHLGNR LTATKEELLK YLGRRINSEM KTKWVSDFIE DLDDEGLRKW
     YGNHPHNFEN GDKEFRFLAR RVVTAAFNSV RRGIVRNRFL NIKAQYIDFL RQVPQYLELQ
     KFSLTENDWQ LHVNQVLERL RAKKLAMADV TPYLYLYDLM TGKHGDRDIR YLFIDEIQDY
     TPYQLSFLKF SFPKARFTLL GDLNQAIFTQ ESSHSLLKEL ATMFQPEDTR VVQLTQSYRS
     TEQITAFTKA ILRNGEAVNA FKRQGPLPNI VVRQQERALL TALKKQLTAN TTANKATAII
     TKTLPESRAL YEKLRAQGIK TTLIQSENQR LASGTIIVPS YLAKGLEFDA VIAWQVNADN
     YHAEDERQLL YTITSRAMHR LTLLVQGTLS PLLTKVPYTT YQLDD
//