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Database: UniProt
Entry: A0A0R2JXR4_9LACO
LinkDB: A0A0R2JXR4_9LACO
Original site: A0A0R2JXR4_9LACO 
ID   A0A0R2JXR4_9LACO        Unreviewed;       141 AA.
AC   A0A0R2JXR4;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   23-MAY-2018, entry version 13.
DE   RecName: Full=Mini-ribonuclease 3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE            Short=Mini-3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE            Short=Mini-RNase 3 {ECO:0000256|HAMAP-Rule:MF_01468};
DE            EC=3.1.26.- {ECO:0000256|HAMAP-Rule:MF_01468};
DE   AltName: Full=Mini-RNase III {ECO:0000256|HAMAP-Rule:MF_01468};
DE            Short=Mini-III {ECO:0000256|HAMAP-Rule:MF_01468};
GN   Name=mrnC {ECO:0000256|HAMAP-Rule:MF_01468};
GN   ORFNames=IV52_GL000747 {ECO:0000313|EMBL:KRN79338.1};
OS   Lactobacillus lindneri DSM 20690 = JCM 11027.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=1122148 {ECO:0000313|EMBL:KRN79338.1, ECO:0000313|Proteomes:UP000051565};
RN   [1] {ECO:0000313|EMBL:KRN79338.1, ECO:0000313|Proteomes:UP000051565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20690 {ECO:0000313|EMBL:KRN79338.1,
RC   ECO:0000313|Proteomes:UP000051565};
RX   PubMed=26415554; DOI=10.1038/ncomms9322;
RA   Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA   Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA   Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O.,
RA   Ritari J., Douillard F.P., Paul Ross R., Yang R., Briner A.E.,
RA   Felis G.E., de Vos W.M., Barrangou R., Klaenhammer T.R.,
RA   Caufield P.W., Cui Y., Zhang H., O'Toole P.W.;
RT   "Expanding the biotechnology potential of lactobacilli through
RT   comparative genomics of 213 strains and associated genera.";
RL   Nat. Commun. 6:8322-8322(2015).
CC   -!- FUNCTION: Involved in correct processing of both the 5' and 3'
CC       ends of 23S rRNA precursor. Processes 30S rRNA precursor
CC       transcript even in absence of ribonuclease 3 (Rnc); Rnc processes
CC       30S rRNA into smaller rRNA precursors. {ECO:0000256|HAMAP-
CC       Rule:MF_01468}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01468};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01468}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01468}.
CC   -!- SIMILARITY: Belongs to the MrnC RNase family. {ECO:0000256|HAMAP-
CC       Rule:MF_01468}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KRN79338.1}.
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DR   EMBL; JQBT01000032; KRN79338.1; -; Genomic_DNA.
DR   RefSeq; WP_054646380.1; NZ_MIYK01000001.1.
DR   EnsemblBacteria; KRN79338; KRN79338; IV52_GL000747.
DR   GeneID; 35783012; -.
DR   PATRIC; fig|1122148.6.peg.770; -.
DR   Proteomes; UP000051565; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.1520.10; -; 1.
DR   HAMAP; MF_01468; RNase_Mini_III; 1.
DR   InterPro; IPR008226; Mini3_fam.
DR   InterPro; IPR000999; RNase_III_dom.
DR   InterPro; IPR036389; RNase_III_sf.
DR   Pfam; PF00636; Ribonuclease_3; 1.
DR   PIRSF; PIRSF005520; UCP005520; 1.
DR   SMART; SM00535; RIBOc; 1.
DR   SUPFAM; SSF69065; SSF69065; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000051565};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Endonuclease {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Nuclease {ECO:0000256|HAMAP-Rule:MF_01468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051565};
KW   Ribosome biogenesis {ECO:0000256|HAMAP-Rule:MF_01468};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_01468};
KW   rRNA processing {ECO:0000256|HAMAP-Rule:MF_01468};
KW   rRNA-binding {ECO:0000256|HAMAP-Rule:MF_01468}.
FT   ACT_SITE     23     23       {ECO:0000256|HAMAP-Rule:MF_01468}.
SQ   SEQUENCE   141 AA;  16417 MW;  BA3EB88C85FB53B8 CRC64;
     MNEAEQNLEF RQLNGVTLAY LGDAVYEVYV RRHLLDNGIT RPNQLQRRAT KYVSAKAQAG
     LIALMEQDEK LNEEEWYFYK RGRNAKSYTH AKNTSVVTYR VSTGFEALFG FLSLSNQQKR
     LDNLAQWCIE QVDNGRVIYE K
//
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