ID A0A0R2JY53_9LACO Unreviewed; 788 AA.
AC A0A0R2JY53;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=DinG family ATP-dependent helicase CPE1197 {ECO:0000313|EMBL:SFV40175.1};
DE SubName: Full=Superfamily II DNA and RNA helicase {ECO:0000313|EMBL:KRN82159.1};
GN ORFNames=IV43_GL001663 {ECO:0000313|EMBL:KRN82159.1}, LAC1533_0755
GN {ECO:0000313|EMBL:SFV40175.1};
OS Ligilactobacillus acidipiscis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=89059 {ECO:0000313|EMBL:KRN82159.1, ECO:0000313|Proteomes:UP000051491};
RN [1] {ECO:0000313|EMBL:KRN82159.1, ECO:0000313|Proteomes:UP000051491}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15353 {ECO:0000313|EMBL:KRN82159.1,
RC ECO:0000313|Proteomes:UP000051491};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
RN [2] {ECO:0000313|EMBL:SFV40175.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACA-DC 1533 {ECO:0000313|EMBL:SFV40175.1};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000190935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACA-DC 1533 {ECO:0000313|Proteomes:UP000190935};
RA Papadimitriou K.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC {ECO:0000256|ARBA:ARBA00038058}.
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DR EMBL; JQBK01000054; KRN82159.1; -; Genomic_DNA.
DR EMBL; LT630287; SFV40175.1; -; Genomic_DNA.
DR RefSeq; WP_010499686.1; NZ_LT630287.1.
DR AlphaFoldDB; A0A0R2JY53; -.
DR STRING; 89059.LAC1533_0755; -.
DR KEGG; laca:LAC1533_0755; -.
DR PATRIC; fig|89059.3.peg.1775; -.
DR OrthoDB; 9765586at2; -.
DR Proteomes; UP000051491; Unassembled WGS sequence.
DR Proteomes; UP000190935; Chromosome i.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.275.40; -; 1.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 1.10.30.20; Bacterial XPD DNA helicase, FeS cluster domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR InterPro; IPR042493; XPD_DNA_FeS.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KRN82159.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 182..442
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
SQ SEQUENCE 788 AA; 91747 MW; 7E9E1BB65C467ED0 CRC64;
MNRKSVGIRQ MVEFVLRGGD LDPASTGSQN TALEGARIHR KLQKEWEKTT KKEVYLKTEF
EAAQEKWLLH GRADALHLKD DKYDEVREIK TSALKFEDLS QNTLTLYFGQ AKVYAYLLME
QNDLEQLKLS LYYFQTTTEK LTIKTIDYTK DEATEFFENL LKEFTWWIEF KAELRSKRNI
SCQKLSFPFP QYRQNQHELS AAVYKTIYSH KRLFVEAPTG TGKTISTLFP TIKALGEKRA
ERIFYFTAKQ STRRVAEETC ALLGDNGLYM HSITLTAKDK ITFAEEQDIA DTENPYFLGY
YDRIKPAMKD ILTNETLLTR EVIEKYAAKH TVDPFEFSLD VSLFCDTIIC DYNYLFDPLV
YLQRFFPEKD PGNIFLIDEA HNLVQRARLM YTKEISSTQL DKLIETYSPQ TKKASRLLDK
MKQLREQFQI LKEPMRNYRQ DSLIVEEEFE GFKNKLQHFT DFINDWLQEH PEDESRQEVL
DYFFQCHSYL KISEFYGPEF RTKLTYEQDQ DELRLKIFCI DPSELIDQQL QLGGGSILFS
ATLSPLGYYQ EILGGKDSSL AYRLPSPFSP ANLAILVPEY IQTTYKKRAE NQANILQALK
MMTSAKKGNY LVFLPSYSYL TTIVTAFCQE YPEQKVAVQK NEMDAKKREQ FLENFQSDLV
EPILGFAVLG GIFSEGIDLK GDRLSGVAII SVGLPPNDPE LDTLKEYYSH QGKDGFQYAY
QLPGINNVFQ AAGRVIRDEQ DHGVVMLIDA RFNQRRYTSF YPPHWQNYHA VYSSTELKTT
LANFWKHK
//
