ID A0A0R2KIX4_9LACO Unreviewed; 224 AA.
AC A0A0R2KIX4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Sortase {ECO:0000313|EMBL:KRN89362.1};
GN ORFNames=IV53_GL000079 {ECO:0000313|EMBL:KRN89362.1};
OS Ligilactobacillus ceti DSM 22408.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1122146 {ECO:0000313|EMBL:KRN89362.1, ECO:0000313|Proteomes:UP000051500};
RN [1] {ECO:0000313|EMBL:KRN89362.1, ECO:0000313|Proteomes:UP000051500}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22408 {ECO:0000313|EMBL:KRN89362.1,
RC ECO:0000313|Proteomes:UP000051500};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRN89362.1}.
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DR EMBL; JQBZ01000016; KRN89362.1; -; Genomic_DNA.
DR RefSeq; WP_027106433.1; NZ_JQBZ01000016.1.
DR AlphaFoldDB; A0A0R2KIX4; -.
DR STRING; 1122146.IV53_GL000079; -.
DR PATRIC; fig|1122146.4.peg.81; -.
DR eggNOG; COG3764; Bacteria.
DR OrthoDB; 1648028at2; -.
DR Proteomes; UP000051500; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd06165; Sortase_A; 1.
DR Gene3D; 2.40.260.10; Sortase; 1.
DR InterPro; IPR005754; Sortase.
DR InterPro; IPR042007; Sortase_A.
DR InterPro; IPR023365; Sortase_dom-sf.
DR NCBIfam; TIGR01076; sortase_fam; 1.
DR Pfam; PF04203; Sortase; 1.
DR SUPFAM; SSF63817; Sortase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000051500};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT ACT_SITE 130
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT ACT_SITE 192
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ SEQUENCE 224 AA; 25078 MW; 92F0623889767D2B CRC64;
MAEKQKNAKK IWLRILTGIL LIVGLALVFN QPIKNFVVNH LIQTDLNAKI NPKKDQDANF
DFSKVEAVDN KKVLQAMFDK QNVIGKMAIP ALNIKLPIFY GLNNQALMHG AGTMHPNQKM
GEGNYCLAGH HMLDPDIVFG PLDKAKKGQK IYLTDGKKIY TYTITQRVTV DETQVQWVDQ
VPGRKLITLV TCASGHVGEP DRVIVRGELT KVTQATDKKL KMFV
//
