ID A0A0R2L5W1_9LACO Unreviewed; 137 AA.
AC A0A0R2L5W1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Effector of murein hydrolase LrgA {ECO:0000313|EMBL:KRN94650.1};
GN ORFNames=IV81_GL001287 {ECO:0000313|EMBL:KRN94650.1};
OS Pediococcus stilesii.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Pediococcus.
OX NCBI_TaxID=331679 {ECO:0000313|EMBL:KRN94650.1, ECO:0000313|Proteomes:UP000051859};
RN [1] {ECO:0000313|EMBL:KRN94650.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18001 {ECO:0000313|EMBL:KRN94650.1};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRN94650.1}.
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DR EMBL; JQBX01000004; KRN94650.1; -; Genomic_DNA.
DR RefSeq; WP_057802048.1; NZ_JQBX01000004.1.
DR AlphaFoldDB; A0A0R2L5W1; -.
DR STRING; 331679.IV81_GL001287; -.
DR PATRIC; fig|331679.3.peg.1314; -.
DR Proteomes; UP000051859; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR InterPro; IPR005538; LrgA/CidA.
DR PANTHER; PTHR33931:SF4; ANTIHOLIN-LIKE PROTEIN LRGA; 1.
DR PANTHER; PTHR33931; HOLIN-LIKE PROTEIN CIDA-RELATED; 1.
DR Pfam; PF03788; LrgA; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000313|EMBL:KRN94650.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000051859};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 137 AA; 15053 MW; 0273339FEC1DBEAD CRC64;
MDNKDKKTPL LVQMGIFAAI LFVSQIISSL FPPTFVVPAP LIGMIILYLL LLTHVVKLSQ
VENLGDSLIG LISFLFIPSG IQLAGSLKLI QNEGVKDVVV TVFATIILLV VITYCGAFFI
KIHRGLEKNM DKRGEQK
//
