ID A0A0R2LFT3_9LACO Unreviewed; 689 AA.
AC A0A0R2LFT3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:KRN97559.1};
GN ORFNames=IV54_GL001328 {ECO:0000313|EMBL:KRN97559.1};
OS Levilactobacillus paucivorans.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Levilactobacillus.
OX NCBI_TaxID=616990 {ECO:0000313|EMBL:KRN97559.1, ECO:0000313|Proteomes:UP000051906};
RN [1] {ECO:0000313|EMBL:KRN97559.1, ECO:0000313|Proteomes:UP000051906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22467 {ECO:0000313|EMBL:KRN97559.1,
RC ECO:0000313|Proteomes:UP000051906};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRN97559.1}.
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DR EMBL; JQCA01000167; KRN97559.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2LFT3; -.
DR STRING; 616990.IV54_GL001328; -.
DR PATRIC; fig|616990.3.peg.1419; -.
DR Proteomes; UP000051906; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd06576; PASTA_Pbp2x-like_1; 1.
DR CDD; cd06575; PASTA_Pbp2x-like_2; 1.
DR Gene3D; 2.20.70.70; -; 1.
DR Gene3D; 3.30.70.2110; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03793; PASTA; 2.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SMART; SM00740; PASTA; 2.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR PROSITE; PS51178; PASTA; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:KRN97559.1};
KW Cell division {ECO:0000313|EMBL:KRN97559.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 570..630
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 631..687
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
SQ SEQUENCE 689 AA; 74294 MW; 2F01B4EAAAACA572 CRC64;
MLILIVGRFS YISIGKKVQN VNLSTSAQKL YTANETLKAR RGTIYDANGQ AIAEDTSVYS
LYVVLDKRQK SVDGQKLYVT NKEKVADVLA KYLPISRKKA LATLNPSSGH PFQVEFGTAG
QNISLTTKQK IQAEHLSGVN FIQQESRLYP NGVFASHLIG LAQAQTNKAG QTTLTGSMGL
EQAFNKELTG TNGSQKIKKD MYGYQLPGTK QKAKKAKNGD NVYTTLDTRL QTLLETEMSQ
VQGQVKANSM NAVLMNANTG AILAATQRPT FNATTKKGLD KVWRNTLVQD AYEPGSTMKI
FTLASSIDSG NYNGNATYQS GKYTIGNQVV PDWNTAGWGT ITYNKGFAVS SNVAMAHLEQ
QMGHKTWKKY IDRFHFLKST KSGLPGELTG SIAFQRPIEQ ADTAFGQGIQ VTVFQMMQAL
SAVSNDGQMM KPYVISKVVD PNTNKTVKAY GPQAVSNPIS ASTAKSVRKH MEDVVYKKYG
IGADYKMSGE RVAVKTGTAQ VSSGKSGYLS GDDNYLYSVA AMVPASHPKY VMYITMKQPH
LGSKTATQLL ASIMKPVMAR ALQEDTETTN TKVNKMPSVT GQSVASANQA LTKAGATVTT
LGTGQKVQKQ SVTAGTTLYR DQRVFISTGG TVALPSLTGW SKGDVVKLAQ IEGLKLNVTG
DGYVTKQSIK AGTTVGSGAT LAVTLRQNK
//
