ID A0A0R2LMK0_9LACO Unreviewed; 432 AA.
AC A0A0R2LMK0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Nucleotidyltransferase DNA polymerase for DNA repair {ECO:0000313|EMBL:KRO02681.1};
GN ORFNames=IV66_GL000106 {ECO:0000313|EMBL:KRO02681.1};
OS Ligilactobacillus pobuzihii.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=449659 {ECO:0000313|EMBL:KRO02681.1, ECO:0000313|Proteomes:UP000051886};
RN [1] {ECO:0000313|EMBL:KRO02681.1, ECO:0000313|Proteomes:UP000051886}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 103219 {ECO:0000313|EMBL:KRO02681.1,
RC ECO:0000313|Proteomes:UP000051886};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRO02681.1}.
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DR EMBL; JQCN01000001; KRO02681.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2LMK0; -.
DR STRING; 449659.IV66_GL000106; -.
DR PATRIC; fig|449659.4.peg.106; -.
DR OrthoDB; 9808813at2; -.
DR Proteomes; UP000051886; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0009432; P:SOS response; IEA:UniProt.
DR CDD; cd01700; PolY_Pol_V_umuC; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11076:SF35; DNA REPAIR PROTEIN HOMOLOG YOBH; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Mutator protein {ECO:0000256|ARBA:ARBA00022457};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022932};
KW Reference proteome {ECO:0000313|Proteomes:UP000051886};
KW Transferase {ECO:0000313|EMBL:KRO02681.1}.
FT DOMAIN 11..202
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 432 AA; 49044 MW; 1B28E6777046B559 CRC64;
MDYSKEPHGV FFLIDNKSFY ASVECSQRGL DPLETPLVVL SEQENTNGGL ILATSPMAKK
LYGISNVSRQ RDLPKNDELL IVPPRMNLYI EKNLEINEIF WHYTKEIDCV PYSIDETILD
LTYSWRLFGN SPKKVAQQIQ RTVRERLGLY TTVGIGSNPL QAKLALDLFA KHASDLVGEL
DYGNFTDKIW PITELTNVWS IGQRTEKHLH QMGIYSMKDL AHTTPYLLKE EMGIIGTQLL
ALAWGIDRTN LEKPVRVKND SLGNSQVLPR DYHKQEEIEV VIQEIGEQVA ARLRKRNKQT
MCVSLSIGFS YASTQKTGKS RFSQQMKIEP TSDGYKLNHY LIQLFRQNWQ QETVRNIAVS
FGKLITTQDL QLNLFTSVKK QEKHVILEKT LDNIRAGFGT KALFFGHSLK QGGTMLDRAG
LIGGHNGGNS YS
//
