ID A0A0R2MB32_9LACO Unreviewed; 1186 AA.
AC A0A0R2MB32;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN ORFNames=IV64_GL000539 {ECO:0000313|EMBL:KRO08451.1};
OS Lactiplantibacillus xiangfangensis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=942150 {ECO:0000313|EMBL:KRO08451.1, ECO:0000313|Proteomes:UP000051783};
RN [1] {ECO:0000313|EMBL:KRO08451.1, ECO:0000313|Proteomes:UP000051783}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 26013 {ECO:0000313|EMBL:KRO08451.1,
RC ECO:0000313|Proteomes:UP000051783};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible hinge near
CC the middle of the molecule. These domains are separated by coiled-coil
CC structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRO08451.1}.
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DR EMBL; JQCL01000080; KRO08451.1; -; Genomic_DNA.
DR RefSeq; WP_057707045.1; NZ_JQCL01000080.1.
DR AlphaFoldDB; A0A0R2MB32; -.
DR STRING; 942150.IV64_GL000539; -.
DR PATRIC; fig|942150.3.peg.552; -.
DR OrthoDB; 9808768at2; -.
DR Proteomes; UP000051783; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03278; ABC_SMC_barmotin; 2.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR NCBIfam; TIGR02168; SMC_prok_B; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Cell cycle {ECO:0000313|EMBL:KRO08451.1};
KW Cell division {ECO:0000313|EMBL:KRO08451.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|HAMAP-
KW Rule:MF_01894};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01894};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01894}; Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01894}.
FT DOMAIN 519..638
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT REGION 300..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 757..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 680..749
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1186 AA; 131900 MW; BEE6E3860B12C433 CRC64;
MQLKSLEISG FKSFADKTKI DFQAGMTGIV GPNGSGKSNI IEAIRWVLGE QAVKSLRGTK
MTDVIFAGSA NRKPLNMAKV TITFDNSDHF LPLDYAEVSI TRKLFRNGDS DYLINNQSCR
LKDITNLMID TGLGKDSFSV ISQGRVEAVF NAKPEDRRSI IEDVAGVLKY KKDKSTTEAK
LAETTDYLDR VNDIIAELAQ QKGPLEQQAS LARDYQDQKQ KYDDLDRSRL VKKMTIAHDQ
LVTVNQKLTG AKTLVAQYQQ QVDAGATKLA TLTAQQAEQR QLKDQLAAKN LELTKTIENT
QGQQGVDAER RQNQQATQSR LQAELANATD QLASLGEQRS QLTAQLSQQR EQIKKLKATV
AELTTATSEA GRKQLADQLT ALRNAYVDEK QVQAELNNEA KNLVKQHQQA GNQTDALAQR
LVTAQANLKR AQTTVDVHNR DQSTLQNQLT QQQTALTQQR EQFKANAVKI DQQQQRWLDA
AGMMQREKSR LEALQSVQER YTNFYAGVRM VLQHRQQFAG VAGAVSELLT VPSSYTKAVE
VALGGQLQNI VCDTQQTAKV VVNFLKQNHA GRATFLPVDR IQARQLAVNT EHELQQQPGV
LGIASELVDC EPQLLAIKRY LLGTTVIVDT LDHAMAISRT RRFRCKLVTV GGETIAASGA
ITGGATRHDD NGLLQQQQSA EKIAANVDQM QGELITYEKD LADAKKANQD LSSQIETNQQ
RLSDLKDQLN QVQAQLQAAQ SEQTQLARQV KALDYEQRQR SQADDSYEDQ VTRNEQAKAD
NDAKLKDYQA QMATVEQQQN DYEAYQKAQS SRLQDQREQL VTLQERCKQT QVQVEQCDQQ
VQQQTQAQAQ ARASLEEIKT DLASQQMSVQ ERASVLKTAQ ASQAKVLQAR KDCDQRLGDL
NDTVEELSDQ QVRNQQLAAA ATDDYRRLEL SQTKLTGEVD HATADLAEKY SLTVEAAKSD
VSDLELPAIN EQLKLLKRGL DEIGTVNLGA IEEFDRVKER YDFLSLQASD LKESKAHLLQ
TMADLDTTVA TRFKTAFDQV AKQFSTIFVQ MFGGGKAELI LTDPEHLLTS GVDIMAQPPG
KKFQRLSLLS GGERALTAIT LLFAILAVRP VPFSILDEAE AALDDANVDR FSQYLNDFQT
GTQFVIITHR KGTMMHADVL YGVTMEESGV SKMVSVSLAD LKNEQN
//
