ID A0A0R2N8N9_9LACO Unreviewed; 433 AA.
AC A0A0R2N8N9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=II DNA RNA helicase {ECO:0000313|EMBL:KRO22182.1};
GN ORFNames=IV88_GL001278 {ECO:0000313|EMBL:KRO22182.1};
OS Pediococcus argentinicus.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Pediococcus.
OX NCBI_TaxID=480391 {ECO:0000313|EMBL:KRO22182.1, ECO:0000313|Proteomes:UP000051249};
RN [1] {ECO:0000313|EMBL:KRO22182.1, ECO:0000313|Proteomes:UP000051249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23026 {ECO:0000313|EMBL:KRO22182.1,
RC ECO:0000313|Proteomes:UP000051249};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- SIMILARITY: Belongs to the DEAD box helicase family.
CC {ECO:0000256|RuleBase:RU000492}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRO22182.1}.
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DR EMBL; JQCQ01000040; KRO22182.1; -; Genomic_DNA.
DR RefSeq; WP_057800382.1; NZ_JQCQ01000040.1.
DR AlphaFoldDB; A0A0R2N8N9; -.
DR PATRIC; fig|480391.4.peg.1297; -.
DR OrthoDB; 9805696at2; -.
DR Proteomes; UP000051249; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProt.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000492};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU000492};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000492};
KW Reference proteome {ECO:0000313|Proteomes:UP000051249}.
FT DOMAIN 25..194
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 220..364
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 377..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..413
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..433
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 433 AA; 48301 MW; 71F316CBA39D411E CRC64;
MNEIFEQHFN EKGFKARTLI QKQTFDLLLD GQSVIGLSPT GSGKTLAFAL PLLEKIIPGD
GIQLLVLSPS QELAVQTTDV FREWASLLKL KVSSVTGGAN LQRQIERLKK KPEIIVGTPG
RVLTLVNEGR LKTSEINTLV VDEADELLVG ETLGDIRQIE DQLPGSLQYG FFSATSADSL
FQISNWFGID PVTVDVRADD HTQGMVKHGW MVTSDASKLK LLRKLSHLKH FQALVFFNHV
STLEKVAATL KHEGVHAGKI AGHQVQTDRA TALRDFRKGK LDLLLVTEVA ARGLDIQKLP
AVINYDVPEK AINYTHRVGR TGRMGESGFV INFGNDHDIR DVKKIGRSLN LEMNSLVIMN
DEVMTSEEAK DVQPIKKTAV KNDNDRQSTR PKARAKIKKT NVQKDSDIRE TPLKKKKHSK
KHSKRKGMRQ KKS
//
