ID A0A0R2NPY4_9LACO Unreviewed; 462 AA.
AC A0A0R2NPY4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN ORFNames=IV88_GL000992 {ECO:0000313|EMBL:KRO26077.1};
OS Pediococcus argentinicus.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Pediococcus.
OX NCBI_TaxID=480391 {ECO:0000313|EMBL:KRO26077.1, ECO:0000313|Proteomes:UP000051249};
RN [1] {ECO:0000313|EMBL:KRO26077.1, ECO:0000313|Proteomes:UP000051249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23026 {ECO:0000313|EMBL:KRO26077.1,
RC ECO:0000313|Proteomes:UP000051249};
RX PubMed=26415554; DOI=10.1038/ncomms9322;
RA Sun Z., Harris H.M., McCann A., Guo C., Argimon S., Zhang W., Yang X.,
RA Jeffery I.B., Cooney J.C., Kagawa T.F., Liu W., Song Y., Salvetti E.,
RA Wrobel A., Rasinkangas P., Parkhill J., Rea M.C., O'Sullivan O., Ritari J.,
RA Douillard F.P., Paul Ross R., Yang R., Briner A.E., Felis G.E.,
RA de Vos W.M., Barrangou R., Klaenhammer T.R., Caufield P.W., Cui Y.,
RA Zhang H., O'Toole P.W.;
RT "Expanding the biotechnology potential of lactobacilli through comparative
RT genomics of 213 strains and associated genera.";
RL Nat. Commun. 6:8322-8322(2015).
CC -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC system (PTS), a major carbohydrate active -transport system, catalyzes
CC the phosphorylation of incoming sugar substrates concomitant with their
CC translocation across the cell membrane.
CC {ECO:0000256|PIRNR:PIRNR006351}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRO26077.1}.
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DR EMBL; JQCQ01000003; KRO26077.1; -; Genomic_DNA.
DR RefSeq; WP_057797989.1; NZ_JQCQ01000003.1.
DR AlphaFoldDB; A0A0R2NPY4; -.
DR PATRIC; fig|480391.4.peg.1007; -.
DR OrthoDB; 1550290at2; -.
DR Proteomes; UP000051249; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR004501; PTS_EIIC_3.
DR InterPro; IPR004796; PTS_IIC_cello.
DR NCBIfam; TIGR00410; lacE; 1.
DR PANTHER; PTHR33989; -; 1.
DR PANTHER; PTHR33989:SF4; PTS SYSTEM N,N'-DIACETYLCHITOBIOSE-SPECIFIC EIIC COMPONENT; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR006351};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW Reference proteome {ECO:0000313|Proteomes:UP000051249};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW ECO:0000256|PIRNR:PIRNR006351};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT TRANSMEM 65..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..427
FT /note="PTS EIIC type-3"
FT /evidence="ECO:0000259|PROSITE:PS51105"
SQ SEQUENCE 462 AA; 49746 MW; 40E4E545A37739EB CRC64;
MNDWINNKLL PPVMKFVNTK AIMAMRDGML FSLPFTMVGS LFLLLSALPV PAWSNWMMSV
GLTPYWTQAF NATMAIMSVF AVIGIAYSWV KNEGFDPLPA GLTGLVSFFL VMRPSTPVMD
GTKTVISAAK APVLLNGGFI DRTWLGGQGM IAAIIIGMLT GLVYTWFVKN NITIKLPDQV
PPAVAGSFTA LVPAAAITAG WLAIYAFFDI TTHSTMVEWI YKVIQTPLQG ITDSFGGVVV
VALLVPFFWF FGVHGAVIVG GIMGPILGSN ALQNAAIVKA HGVAGLTAAN GAHVFTQSLL
DQFGTVTGSG MTIGLVVFMA FFAKSEQMKS IGRLSFLPGV FNINEPVLFG VPVVLNPLLA
VPFMIMPLLS MGSTYWLIKL GVLPYLTGVQ VPWTTPAIIS GFFVGGWKIA LWQAIMLVLS
FFVYFFFARK QDQILFAQEQ AAGNADHAEE AKDAATKEKA TA
//
