ID A0A0R2SXY8_9GAMM Unreviewed; 500 AA.
AC A0A0R2SXY8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Sodium:proton exchanger {ECO:0000313|EMBL:KRO79801.1};
GN ORFNames=ABR85_02195 {ECO:0000313|EMBL:KRO79801.1};
OS OM182 bacterium BACL3 MAG-120619-bin3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; OMG group; OM182 clade.
OX NCBI_TaxID=1655593 {ECO:0000313|EMBL:KRO79801.1, ECO:0000313|Proteomes:UP000051242};
RN [1] {ECO:0000313|EMBL:KRO79801.1, ECO:0000313|Proteomes:UP000051242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BACL22 MAG-120619-bin3 {ECO:0000313|EMBL:KRO79801.1};
RA Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA Andersson A.F.;
RT "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRO79801.1}.
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DR EMBL; LICD01000140; KRO79801.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2SXY8; -.
DR Proteomes; UP000051242; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR PANTHER; PTHR43478; NA+/H+ ANTIPORTER-RELATED; 1.
DR PANTHER; PTHR43478:SF1; NA_H_ANTIPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 259..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 162..471
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 500 AA; 52605 MW; C92943A35FBD5805 CRC64;
MPPETLSDLG VISLLPVALA LVLSIASRNV ILGLFIGLFT GVLLVEGFSP IAALTLMVRD
YLVPQVTDSY NAGVLVLLAF IGGFVALMEK SGGGAAFAAR VMRFITTRAR LQVAAWLGGI
LIFFSDLGTP LIIGPTFRPL ADSLRVSRAK LAYIIDSTAS PVAILVPFIG WGVYIMGLLN
QQIESLGLDA SDYALLLSAL PFQLYAWLAL AAVPLLAIVG VEFGPMRRAE DTARAGNPLQ
QPNDSALEQV TLANARPSFV WLPLVVLGVT LFWVLGPLGF PFGRVSGSDF RAGLATAYLL
AALTLVALMA LNRAQSPLRS LQVYLDGMSR MMQIAIMLLL AWAMGDMMTT LGADDFVATL
VRDNVAAWIL PLLIFVVSCA ISFATGSSWG TFAIMLPLAM PAAFAIDAPL AVCVGAVLSG
GLFGDHCSPI SETTILSSAG AGADVFDHFQ TQLPYALANG ALCVAGFVVA GLSGSVIVLP
VLLSIQIIGM LAFKRLSTAR
//
