ID A0A0R2TB87_9FLAO Unreviewed; 427 AA.
AC A0A0R2TB87;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Na+ dependent nucleoside transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=ABR87_03020 {ECO:0000313|EMBL:KRO82403.1};
OS Cryomorphaceae bacterium BACL7 MAG-121220-bin83.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Cryomorphaceae.
OX NCBI_TaxID=1655595 {ECO:0000313|EMBL:KRO82403.1, ECO:0000313|Proteomes:UP000051535};
RN [1] {ECO:0000313|EMBL:KRO82403.1, ECO:0000313|Proteomes:UP000051535}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BACL29 MAG-121220-bin83 {ECO:0000313|EMBL:KRO82403.1};
RA Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA Andersson A.F.;
RT "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRO82403.1}.
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DR EMBL; LICF01000028; KRO82403.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R2TB87; -.
DR Proteomes; UP000051535; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR PANTHER; PTHR10590:SF4; SOLUTE CARRIER FAMILY 28 MEMBER 3; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..81
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 93..192
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 205..424
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 427 AA; 45718 MW; 1FAD9D480AFF743D CRC64;
MEILRALGSL VLIFGILVLA SANRRAISWS IVVKGMLIQF GLAFLILEVD QISALFDRVG
KGFVALLGFA REGSLFLFGD LVGRVDSFGY IFAFQVLPTI IFFSAITSLL FHFGILQRVV
WVFAWFMKRT LKLSGAESLS AAANVFVGQT EAPLLVKPYI AGMTRSELLC LMSGGMSTIA
GAVLAAYINY LGGTDEARQI FFARHLLAAS VMSAPAAIVA AKILMPETET FVDTAEVKIE
KQGNWLEAIA HGTADGLKMA VNVGVMLLVF TALIALVNAL MSGALGEWTG LNEWLADVTE
GRYTEFNLQA LFGLTLAPLT WLMGVPWSDA AAVGQLLGEK TVLNEFYAYV SMGTLMENGQ
LTSEKAQILS TYILCGFANF ASIGIQIGGI GALAPSRRKD LSQLGLRALL AGTAASLLTA
ILVGLLY
//
