ID   A0A0R2XP45_9BACT        Unreviewed;       435 AA.
AC   A0A0R2XP45;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=O-acetylhomoserine aminocarboxypropyltransferase {ECO:0000313|EMBL:KRP37944.1};
DE            EC=2.5.1.49 {ECO:0000313|EMBL:KRP37944.1};
GN   ORFNames=ABS34_00365 {ECO:0000313|EMBL:KRP37944.1};
OS   Opitutaceae bacterium BACL24 MAG-120322-bin51.
OC   Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae.
OX   NCBI_TaxID=1655636 {ECO:0000313|EMBL:KRP37944.1, ECO:0000313|Proteomes:UP000054041};
RN   [1] {ECO:0000313|EMBL:KRP37944.1, ECO:0000313|Proteomes:UP000054041}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BACL24 MAG-120322-bin51 {ECO:0000313|EMBL:KRP37944.1};
RA   Hugerth L.W., Larsson J., Alneberg J., Lindh M.V., Legrand C., Pinhassi J.,
RA   Andersson A.F.;
RT   "Metagenome-Assembled Genomes uncover a global brackish microbiome.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRP37944.1}.
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DR   EMBL; LIDO01000002; KRP37944.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R2XP45; -.
DR   Proteomes; UP000054041; Unassembled WGS sequence.
DR   GO; GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   CDD; cd00614; CGS_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; TIGR01326; OAH_OAS_sulfhy; 1.
DR   PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR   PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR001434-2};
KW   Transferase {ECO:0000313|EMBL:KRP37944.1}.
FT   MOD_RES         210
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ   SEQUENCE   435 AA;  46808 MW;  2783431829D672DB CRC64;
     MTDKKAAALG TLALHAGHTP DAETGSRAVP IYQTTSYMFR DTDHAAKLFG LEELGYIYTR
     IMNPTTDVLE KRVAALEGGV AGLAHASGQA AITSAILNIA GAGDNIVSSA QLYGGTYTLF
     KYTLPKLGIE VRFANAEDAS SFEPLIDEKT KAIYGDTVGN PKLNIFPFEE VSAVARAAKI
     PLIIDNTVAS PMICRPLEHG ANVVVHSLTK YIGGHGTSIG GIVIDGGNFD WGSGRFTEFT
     EPDPSYHGLV HWDVFKAFEP AGGANIAYIM KMRLQWLRDT GNCTSPFNSF LHIQGLETLH
     LRMQRHCSNA LKVAQFLESH EAVSWVNYPG LSESTQHAAA AKYFDKDSFG GLVGFGLKGG
     LEAGRKFIDS LELFSHLANI GDAKSLAIHP ASTTHQQLTE EQQQSTGVTA DFVRLSVGIE
     AIEDLLADLD HALKA
//