GenomeNet

Database: UniProt
Entry: A0A0R3NLR4_DROPS
LinkDB: A0A0R3NLR4_DROPS
Original site: A0A0R3NLR4_DROPS 
ID   A0A0R3NLR4_DROPS        Unreviewed;      1698 AA.
AC   A0A0R3NLR4;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   31-JUL-2019, entry version 19.
DE   SubName: Full=Uncharacterized protein, isoform C {ECO:0000313|EMBL:KRT01886.1};
GN   Name=Dpse\GA24436 {ECO:0000313|EMBL:KRT01886.1};
GN   ORFNames=Dpse_GA24436 {ECO:0000313|EMBL:KRT01886.1}, GA24436
GN   {ECO:0000313|FlyBase:FBgn0245833};
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245 {ECO:0000313|EMBL:KRT01886.1, ECO:0000313|Proteomes:UP000001819};
RN   [1] {ECO:0000313|EMBL:KRT01886.1, ECO:0000313|Proteomes:UP000001819}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94
RC   {ECO:0000313|Proteomes:UP000001819};
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P.,
RA   Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J.,
RA   van Batenburg M.F., Howells S.L., Scherer S.E., Sodergren E.,
RA   Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D.,
RA   Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D.,
RA   Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R.,
RA   Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L.,
RA   Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura:
RT   chromosomal, gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
RN   [2] {ECO:0000313|EMBL:KRT01886.1, ECO:0000313|Proteomes:UP000001819}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94
RC   {ECO:0000313|Proteomes:UP000001819};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 Genomes Consortium;
RA   Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B.,
RA   Markow T.A., Kaufman T.C., Kellis M., Gelbart W., Iyer V.N.,
RA   Pollard D.A., Sackton T.B., Larracuente A.M., Singh N.D., Abad J.P.,
RA   Abt D.N., Adryan B., Aguade M., Akashi H., Anderson W.W.,
RA   Aquadro C.F., Ardell D.H., Arguello R., Artieri C.G., Barbash D.A.,
RA   Barker D., Barsanti P., Batterham P., Batzoglou S., Begun D.,
RA   Bhutkar A., Blanco E., Bosak S.A., Bradley R.K., Brand A.D.,
RA   Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA   Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA   Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA   Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A.,
RA   Daub J., David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H.,
RA   Edwards K., Eickbush T., Evans J.D., Filipski A., Findeiss S.,
RA   Freyhult E., Fulton L., Fulton R., Garcia A.C., Gardiner A.,
RA   Garfield D.A., Garvin B.E., Gibson G., Gilbert D., Gnerre S.,
RA   Godfrey J., Good R., Gotea V., Gravely B., Greenberg A.J.,
RA   Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A., Haerty W.,
RA   Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA   Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A.,
RA   Hubisz M.J., Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S.,
RA   Jeck W.R., Johnson J., Jones C.D., Jordan W.C., Karpen G.H.,
RA   Kataoka E., Keightley P.D., Kheradpour P., Kirkness E.F.,
RA   Koerich L.B., Kristiansen K., Kudrna D., Kulathinal R.J., Kumar S.,
RA   Kwok R., Lander E., Langley C.H., Lapoint R., Lazzaro B.P., Lee S.J.,
RA   Levesque L., Li R., Lin C.F., Lin M.F., Lindblad-Toh K., Llopart A.,
RA   Long M., Low L., Lozovsky E., Lu J., Luo M., Machado C.A.,
RA   Makalowski W., Marzo M., Matsuda M., Matzkin L., McAllister B.,
RA   McBride C.S., McKernan B., McKernan K., Mendez-Lago M., Minx P.,
RA   Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E., Negre B.,
RA   Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA   Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S.,
RA   Pesole G., Phillippy A.M., Ponting C.P., Pop M., Porcelli D.,
RA   Powell J.R., Prohaska S., Pruitt K., Puig M., Quesneville H.,
RA   Ram K.R., Rand D., Rasmussen M.D., Reed L.K., Reenan R., Reily A.,
RA   Remington K.A., Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H.,
RA   Rohde C., Rozas J., Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L.,
RA   Sanchez-Gracia A., Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C.,
RA   Schlenke T., Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M.,
RA   Sisneros N.B., Smith C.D., Smith T.F., Spieth J., Stage D.E.,
RA   Stark A., Stephan W., Strausberg R.L., Strempel S., Sturgill D.,
RA   Sutton G., Sutton G.G., Tao W., Teichmann S., Tobari Y.N.,
RA   Tomimura Y., Tsolas J.M., Valente V.L., Venter E., Venter J.C.,
RA   Vicario S., Vieira F.G., Vilella A.J., Villasante A., Walenz B.,
RA   Wang J., Wasserman M., Watts T., Wilson D., Wilson R.K., Wing R.A.,
RA   Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G., Yamamoto D.,
RA   Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E., Zhang P.,
RA   Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA   Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A.,
RA   An P., Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P.,
RA   Barry A., Bayul T., Berlin A., Bessette D., Bloom T., Blye J.,
RA   Boguslavskiy L., Bonnet C., Boukhgalter B., Bourzgui I., Brown A.,
RA   Cahill P., Channer S., Cheshatsang Y., Chuda L., Citroen M.,
RA   Collymore A., Cooke P., Costello M., D'Aco K., Daza R., De Haan G.,
RA   DeGray S., DeMaso C., Dhargay N., Dooley K., Dooley E., Doricent M.,
RA   Dorje P., Dorjee K., Dupes A., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Fisher S., Foley C.D., Franke A., Friedrich D.,
RA   Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA   Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA   Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA   Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA   Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F.,
RA   LeVine R., Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T.,
RA   Lokyitsang Y., Lubonja R., Lui A., MacDonald P., Magnisalis V.,
RA   Maru K., Matthews C., McCusker W., McDonough S., Mehta T., Meldrim J.,
RA   Meneus L., Mihai O., Mihalev A., Mihova T., Mittelman R., Mlenga V.,
RA   Montmayeur A., Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T.,
RA   Nguyen N., Nicol R., Norbu C., Norbu N., Novod N., O'Neill B.,
RA   Osman S., Markiewicz E., Oyono O.L., Patti C., Phunkhang P.,
RA   Pierre F., Priest M., Raghuraman S., Rege F., Reyes R., Rise C.,
RA   Rogov P., Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L.,
RA   Shih D., Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- DOMAIN: The CKK domain binds microtubules. {ECO:0000256|PROSITE-
CC       ProRule:PRU00841}.
CC   -!- SIMILARITY: Belongs to the CAMSAP1 family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00841}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CM000071; KRT01886.1; -; Genomic_DNA.
DR   RefSeq; XP_015039448.1; XM_015183962.1.
DR   EnsemblMetazoa; FBtr0366268; FBpp0329466; FBgn0245833.
DR   GeneID; 6898302; -.
DR   FlyBase; FBgn0245833; Dpse\GA24436.
DR   Proteomes; UP000001819; Chromosome 3.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR   GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0030507; F:spectrin binding; IEA:InterPro.
DR   GO; GO:0031175; P:neuron projection development; IEA:InterPro.
DR   Gene3D; 3.10.20.360; -; 1.
DR   InterPro; IPR032940; CAMSAP.
DR   InterPro; IPR031372; CAMSAP_CC1.
DR   InterPro; IPR022613; CAMSAP_CH.
DR   InterPro; IPR001715; CH-domain.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR038209; CKK_dom_sf.
DR   InterPro; IPR014797; CKK_domain.
DR   InterPro; IPR011033; PRC_barrel-like_sf.
DR   PANTHER; PTHR21595; PTHR21595; 2.
DR   Pfam; PF17095; CAMSAP_CC1; 1.
DR   Pfam; PF11971; CAMSAP_CH; 1.
DR   Pfam; PF08683; CAMSAP_CKK; 1.
DR   SMART; SM01051; CAMSAP_CKK; 1.
DR   SUPFAM; SSF47576; SSF47576; 1.
DR   SUPFAM; SSF50346; SSF50346; 1.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS51508; CKK; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001819};
KW   Microtubule {ECO:0000256|PROSITE-ProRule:PRU00841};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001819}.
FT   DOMAIN      157    289       Calponin-homology (CH).
FT                                {ECO:0000259|PROSITE:PS50021}.
FT   DOMAIN     1556   1691       CKK. {ECO:0000259|PROSITE:PS51508}.
FT   REGION      311    331       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      360    388       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      417    507       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      524    620       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      757    865       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      926    983       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1013   1033       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1086   1255       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1271   1308       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1350   1529       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED      637    671       {ECO:0000256|SAM:Coils}.
FT   COILED      701    735       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS    417    433       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    461    481       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    482    503       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    532    547       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    548    575       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    590    619       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    757    855       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    926    954       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1086   1147       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1148   1182       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS   1206   1227       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1236   1255       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1292   1308       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1350   1413       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS   1416   1432       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1451   1513       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   1698 AA;  191915 MW;  7351A846D94FC83A CRC64;
     MDAAESQEIR QARQRASVKW LLSKAFNNRV PDNLKEPFYR DHENQERLKP QIIVELGNAT
     LYCQTLSNLY SDPNYQSLNH WSIIQTLARK GVPVAESSDM PITETVLIQT NPLRINAHMS
     VIESLMVLYA KEISSGDRIM SAIRRISGSN YQTPPGQTYE QALLAWISHA CAALKKRIIK
     EVETGLPDEN GTRLQTPDIP PVRDFQDLCD GICLALLIAY YCPKVVPWTM VRINYLPAVE
     DSIHNILLVS NFSQKHLPYG VFHMTPEDVT FMRGSMKLNL VLLLTDLFNL FEIHPAKCVC
     YPGMDGQVPH SNSFSGGLNR RSTPPNEHQH QQAVVQANSN HFDGNQGEAF VVHKSRGITT
     LSSMHSQQQQ QHHHQQQHQQ QQQFHQQQQS QLQQQLQQQQ QQQQQQEPLV PARLRQAKEK
     TNVESKADER GDFVAAGRPS NWEQSRRPSF AGRRSRRNSS SEDSQLTIEN FGGSQDQLNT
     LGGRFDRDRE RDRDRDRERK LSNTSIAEPA VAVRSSIADA RGTLQLGYDT DSGSEKQDRE
     TEKYSMRRQA SVDNVPTVSA HNLSNASSPL PQARNKQHSS DKDYSHSVAD TYNDARSSAY
     DPESTPVRKS STSSMPASPA AWQLEVGDED MRSLENATKL STIRMKLEEK RRRIEQDKRK
     IEMALLRHQE KEDLESCPEV MKWETMSNES KRTPDMDPVD LDKYQQSIAI MNMNLQDIQQ
     DIHRLATQQS QMQAQHLQAQ QLLQAQQIAN MLNQQQTYGS QQHLSDHHYQ QQQRPMQQSF
     GSSPHLPQAY NAPVSAYSSR PPSRDPYQQQ HQQQQPMAMP QPMQFVNEHG QYMSPPQPSH
     YQPQSIYSDN GAPYNNHSPH YGAAAPPQYR SSVVFDDYGQ PTNHFYLHES SPQAQPQGHP
     QRRTWAHSAA AAAYEQQQQI QQPMVDVNAW QSQQQQQQHH QQQKKAQQPW MNRPPSSAGG
     AAQGSFMLHQ NGGGGGGGGG GELQHLFQVQ ASPQHSQRQL GGGANGVQRQ QSLTNLRDNR
     SPKSQHQPQT MGMAMQQEDM MAPQSICFIG DEEDVDEVER NIIESMQATR ISDFVLQQQQ
     QQQHHQQQLQ LQQQQQRLQG GRGSSSEDYD SGEMISNKLN ITSGNLTYRI PSPSRPSIQA
     NSFQDPRDSE DQPAEKGFYI SFDDDQPKRP KPPLRAKRSP KKEALPLGGS SSSIRDRDSV
     DHQTLLKRES LSQLHNNNNN NGSEDGHKSA GANRHSIHGL NHSNSVKSPG NATYNKYTDE
     APIQLRHLAV SGSDPFGHEP HPHPHPQPMQ QQPMSPTRIQ QSNNSAEAAK NKALVIGADA
     TNLDPESVDE MERRKEKIML LSLQRRQQQE EAKARKEIEA SQKREKEREK EEERARKKED
     QMARRAAILE QHRLKKAIEE AEREGKTLDR PDLHVKLQPQ SSSATNPRLR QQRTTRPRPK
     TIHVDDASVD ISEASSISSR GKKGSSSNLT GYGQLSSNSM KRDYYRGSQD SLTVKESPDD
     YPSTSSTPIG RRGSYKTSRE PAAVERGRTL SRISVAKGST LNFRGRKSNS LMNLCGPKLY
     KQPAAKSNRG IILNAVEYCV FPGAVNREAK QKVLEKIARS EAKHFLVLFR DAGCQFRALY
     SYMPESGDQV TKLYGTGPSQ VDEVMFDKFF KYNSGGKCFS QVHTKHLTVT IDAFTIHNSL
     WQGKRVQLPS KKDMALVI
//
DBGET integrated database retrieval system