ID   A0A0R3NRA2_DROPS        Unreviewed;      2073 AA.
AC   A0A0R3NRA2; A0A6I8V7Q5;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Dedicator of cytokinesis protein 7 isoform X1 {ECO:0000313|RefSeq:XP_015035620.1};
GN   Name=LOC4817744 {ECO:0000313|RefSeq:XP_015035620.1};
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245 {ECO:0000313|Proteomes:UP000001819, ECO:0000313|RefSeq:XP_015035620.1};
RN   [1] {ECO:0000313|RefSeq:XP_015035620.1}
RP   IDENTIFICATION.
RC   STRAIN=MV2-25 {ECO:0000313|RefSeq:XP_015035620.1};
RC   TISSUE=Whole body {ECO:0000313|RefSeq:XP_015035620.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00983}.
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DR   RefSeq; XP_015035620.1; XM_015180134.2.
DR   STRING; 46245.A0A0R3NRA2; -.
DR   EnsemblMetazoa; FBtr0374712; FBpp0336253; FBgn0071013.
DR   GeneID; 4817744; -.
DR   InParanoid; A0A0R3NRA2; -.
DR   Proteomes; UP000001819; Chromosome 4.
DR   Bgee; FBgn0071013; Expressed in insect adult head and 2 other cell types or tissues.
DR   ExpressionAtlas; A0A0R3NRA2; baseline.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:EnsemblMetazoa.
DR   GO; GO:0035011; P:melanotic encapsulation of foreign target; IEA:EnsemblMetazoa.
DR   GO; GO:0006909; P:phagocytosis; IEA:EnsemblMetazoa.
DR   GO; GO:0035023; P:regulation of Rho protein signal transduction; IEA:EnsemblMetazoa.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd08696; C2_Dock-C; 1.
DR   CDD; cd11695; DHR2_DOCK_C; 1.
DR   Gene3D; 1.20.58.740; -; 1.
DR   Gene3D; 1.25.40.410; -; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR037808; C2_Dock-C.
DR   InterPro; IPR027007; C2_DOCK-type_domain.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR026791; DOCK.
DR   InterPro; IPR021816; DOCK_C/D_N.
DR   InterPro; IPR043161; DOCK_C_lobe_A.
DR   InterPro; IPR043162; DOCK_C_lobe_C.
DR   InterPro; IPR027357; DOCKER_dom.
DR   InterPro; IPR046769; DOCKER_Lobe_A.
DR   InterPro; IPR046770; DOCKER_Lobe_B.
DR   InterPro; IPR046773; DOCKER_Lobe_C.
DR   PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR   PANTHER; PTHR23317:SF76; LD20667P; 1.
DR   Pfam; PF06920; DHR-2_Lobe_A; 1.
DR   Pfam; PF20422; DHR-2_Lobe_B; 1.
DR   Pfam; PF20421; DHR-2_Lobe_C; 1.
DR   Pfam; PF14429; DOCK-C2; 1.
DR   Pfam; PF11878; DOCK_C-D_N; 1.
DR   PROSITE; PS51650; C2_DOCK; 1.
DR   PROSITE; PS51651; DOCKER; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001819}.
SQ   SEQUENCE   2073 AA;  235943 MW;  DB3E55E9D85A2AF2 CRC64;
     MSNAQRSFVQ KVSKQPAADV RKNVCNYHIQ SKSADTSLCS SALSPTDPLD YEEFLVQHMN
     IVNRDPLKLI LDFPQGDVTV KTIPRKIRTI DHITPNEEIT DLPQHVQECV NCYTRPWKVV
     EYAQRHYSSS CYIREHIDRG TISPSAYQQE FEIDKDFASF DETFTYKSES CTPSSRQSIA
     SLASVSSCTD TLTPRGSWAS FDLRRSVNDP LIPNLLNNVP PEQIDQTNEV RRQQDRQVAL
     FSLYPESEAE EERIERRLLA EIPMEHMGHR IQVKCLQLRL ELEVEPIFAS MALYDAKERQ
     KLSENFYFDM NSDGLKRMLS SHVQCADIST QSHSAIFEVS YPSNDLFLVI RLEKVLQGDI
     NNSVEPYLKE DKDKYREKVK SNAADYCERL GKYRMPFAWT GIYLTNVFNG DSFEHKDVGG
     GERDSAGSGN VCGGLGTAPS SNSLDRKSST SSFDQLRRKA NDMSGTLTRR GSLERKEKRR
     SWSPDDFANV VENFRPITIS VPSFFKQEAD KMKDEDLYKI LPELKRPSSV MKKYKCIPGS
     IKLEISPCVE EVKNSLTPEL AKINPQSGEN IRPIKEILEF PQSAIYNPHY SYRNLLFVSP
     KELNFSSRAG SARNIAVRVQ LMAGETSKDA VNAIFGKSSC PKFSSEAFTA VNYHNKCPSF
     YDEIKIALPA SIKQHHHLLF TIYHVSCQKK PQDLQPSVET PIGYTWLPLL EDGKLKVGEF
     NLPVMVETPP ENYSFIPPNV HLPGIKWLDN HRAVFAINVE AVTAIHTLDS FLDRFFLLCE
     YVDTRNIPSH IGEGNMEAEL KKCLLDIEHA NREPLVRHLP LVLDKLIELL VTTHKIGGQT
     MSLGSTVFEV LCLVSSLLSI LSDDLIVDQY GRQSLFSTYV QFQCKIPHPL LSKQRFTCRR
     SNTEDLQLSN SYSLYDNVST SGRSLDRKDP AINMLHSIVG RDVQERLLHE ELALHWVVAS
     GKAAELAMAN SWFLFELIVK SMIEHLHNSN TLNAPRKNRF PHQYNDDLST LVHLVTTKVV
     GYHSNEPKLA QSLNASLSFF IFDVLSIMDR GFVFGLIKTY TKVLISKNAS IPDLMNYKID
     FLRIVCSHEH FVALNLPFGT SYTMISAPCS PTPSTTSSNS QTSCGSLERA VQADLSQEFL
     QQHFLVGLVL SDLASVMKVP NPQLHGKAIR CIRNLMTSHD LDTRYSETEA RARVASLYIP
     LLFIVMDSIP QLHQHGIDHD RLHQIGQLED YQGPQQTIAA ATISPEVAYA ISGSRPYYMS
     EQVKNKSPLS SENTRHLLVC FLWVLKNLER NILYRWLLGL TPHRVHQMLQ VVNVCLKTFE
     YTGQKYIPTL KRTNTQSFRK NASTDVKEKL EECIRGTNSA RYDLINRRKD RNSTEKFRWR
     KDQMPYRSPY TDSVGKNEHD LELSHFIEGS LATEITLVLL DTLEILVHVA ANIHHNLLGT
     LLKVLLHALS RNQSTLALQN LFASQRALIF KFPNLLFDEE TDICADLCLI LLKHCGSLLP
     GIRSQAAASL YLLMRQNFEI GNNFARVKMQ VTMSLSSLVG TSTVFSEQSL RRALKTVLVY
     AESDSDLQDT SFPEQVQDLL FNLHMILSDT VKMKEYQEDP EMLLDLMNRI AKGYQNNPDL
     RLTWLENMAK KHRERANHTE AAMCYVHAAA LVSEYLSMLE SQTHLPVGAV SFQRISPNTL
     MESAVSDDVL SPGEDGICLG NHFTETGLKA LLEEASNSFQ VAGMYEAMNE VYKILIPICE
     ANRDFLKLGK VHGKLQEAFN RISQLQGKRV FGTYFRVGFY GSKFGDLDQQ EFIYKEPTLT
     KLPEIFSRLQ NFYTERFGPD SVHIIKDSNT VDVNSLDAEK AYIQITYVEP YFETYEMRHR
     ETYFERNFNI KRFIYATPFT KSGKAHGELH EQCKRKTILT TANHFPYVKT RIMVISRQQI
     VLDPIEVAIE DIQKKTVELA AATNQEPADP KILQMVLQGC IGTTVNQGPM EMASVFLLNL
     SDGTTVPTKQ QNKLRLCFRE FSKRCADALK KNRNLILSDQ KDYQRELERN NDRFIERLTP
     LITLTAIQNL GVVKANAYYN KSTPLKCVSD YFK
//