ID   A0A0R3P9E5_ANGCS        Unreviewed;       428 AA.
AC   A0A0R3P9E5;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Zinc transporter ZIP3 {ECO:0000256|ARBA:ARBA00039395};
DE   AltName: Full=Solute carrier family 39 member 3 {ECO:0000256|ARBA:ARBA00042778};
DE   AltName: Full=Zrt- and Irt-like protein 3 {ECO:0000256|ARBA:ARBA00041702};
GN   ORFNames=ACOC_LOCUS19 {ECO:0000313|EMBL:VDM51604.1};
OS   Angiostrongylus costaricensis (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC   Angiostrongylus.
OX   NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0000001801-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ACOC_0000001801-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDM51604.1, ECO:0000313|Proteomes:UP000267027}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Costa Rica {ECO:0000313|EMBL:VDM51604.1,
RC   ECO:0000313|Proteomes:UP000267027};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Zn(2+)(in) = Zn(2+)(out); Xref=Rhea:RHEA:29351,
CC         ChEBI:CHEBI:29105; Evidence={ECO:0000256|ARBA:ARBA00036307};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:29352;
CC         Evidence={ECO:0000256|ARBA:ARBA00036307};
CC   -!- SUBCELLULAR LOCATION: Apical cell membrane
CC       {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004424}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; UYYA01000001; VDM51604.1; -; Genomic_DNA.
DR   STRING; 334426.A0A0R3P9E5; -.
DR   WBParaSite; ACOC_0000001801-mRNA-1; ACOC_0000001801-mRNA-1; ACOC_0000001801.
DR   OMA; EDPPILM; -.
DR   Proteomes; UP000050601; Unplaced.
DR   Proteomes; UP000267027; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006829; P:zinc ion transport; IEA:UniProt.
DR   InterPro; IPR003689; ZIP.
DR   PANTHER; PTHR11040:SF214; ZINC TRANSPORTER ZIP3; 1.
DR   PANTHER; PTHR11040; ZINC/IRON TRANSPORTER; 1.
DR   Pfam; PF02535; Zip; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000267027};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        243..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        276..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        303..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        339..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        372..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   428 AA;  47473 MW;  867D59DAABB9C8CF CRC64;
     MNLNTLKLVL LSVMICSTLF AGLSPLKVLR YLRHSAARAS SSKQHKHVSL ILCLLTCFSG
     GWLHSWLPLV LSSLHGTSGV FLATCFLHLF PELVENVGKL DEVYDFYIDY PVAELLSCLG
     FFLLFFLEEH PSVRQIHKVT VFRRHYFHAL NSVEVHSTYT TDHVKGVTSD DENVDGHCQK
     HCPLTVHRVK KSTDHKEPQC TAVSDVYTTL AVAEPERCET NCEKVDEDPP ILMKSSPHAH
     SHGVRSITFV LALSIHSVIE GIAFGVGDNA SETTALFLSL LVHKLIVSFS VGLQLARTHA
     HQLHWVVASV FILALMSPLG AVVGMVVQSA AANSFSKDVA ITILQGLAVG TFLYVTFFEV
     LLHERDNEHP NLLKLLVMLV GFSLIGLLRL IDNHDHSDFS HSLENGSSLA VPRGANYGHH
     RHHHDHIH
//