ID A0A0R3P9X2_ANGCS Unreviewed; 565 AA.
AC A0A0R3P9X2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Eukaryotic translation initiation factor 5B {ECO:0000256|ARBA:ARBA00013824};
DE AltName: Full=Translation initiation factor IF-2 {ECO:0000256|ARBA:ARBA00032478};
GN ORFNames=ACOC_LOCUS263 {ECO:0000313|EMBL:VDM51848.1};
OS Angiostrongylus costaricensis (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0000026201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ACOC_0000026201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM51848.1, ECO:0000313|Proteomes:UP000267027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Costa Rica {ECO:0000313|EMBL:VDM51848.1,
RC ECO:0000313|Proteomes:UP000267027};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UYYA01000022; VDM51848.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3P9X2; -.
DR STRING; 334426.A0A0R3P9X2; -.
DR WBParaSite; ACOC_0000026201-mRNA-1; ACOC_0000026201-mRNA-1; ACOC_0000026201.
DR OMA; FRQSKPA; -.
DR Proteomes; UP000050601; Unplaced.
DR Proteomes; UP000267027; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-KW.
DR CDD; cd03703; aeIF5B_II; 1.
DR CDD; cd16266; IF2_aeIF5B_IV; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR029459; EFTU-type.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR43381:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 5B; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF14578; GTP_EFTU_D4; 1.
DR Pfam; PF11987; IF-2; 1.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000267027}.
FT DOMAIN 1..191
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 565 AA; 63811 MW; 4710F75C6E2CC0C0 CRC64;
MLDTIRRTNV QDGEAGGITQ QIGATPRKLC VSVSSQLIYW RNTPSFFNYS LCGYLNLRSR
GSSLCDFAIL VVDITHGLEP QTIESLKLLL KRKTPFVIAL NKIDRLYGYE SNPRKDVYQH
LKSQPQNTQL EFKERYQKIV GEFSEQAINV CLSNQNKNLD EYISMVPTSA VLGDGIGNLI
SYIVFATQTY HADKLSFCEE LDATVMEVKA IPGLGTTIDV ILVNGWLRVG DIIVVTGSDG
AIMTPIRELL MPQPLRELRV KNEYGHYKEI QGAQGVKILA KGLERALAGL PLFVAHKEDE
IDFLKYEAES QLSRALMSIK KKPEGVYVQA STLGSLEALL DFLKTQKIPY SNVNIGPVHK
KDVQKAAAML EHRAEYACIL AFDVKVEREA QLFADQEKVK IFQADIIYHL EDSFLKYREE
LRLRARKENE HLAIFPCKLR ILPQNVFNAR NPIVCGVSVE AGQLKRGTPI CVPSRDCVFL
GTVASIERNH EEMQLAKTGD EVCIKIENTT GEAPKLYGRH FNHEDILVSR ISRDSIDACK
TYFRDDLSRA DWQLVVELKR LLDIL
//
