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Database: UniProt
Entry: A0A0R3PBE0_ANGCS
LinkDB: A0A0R3PBE0_ANGCS
Original site: A0A0R3PBE0_ANGCS 
ID   A0A0R3PBE0_ANGCS        Unreviewed;       175 AA.
AC   A0A0R3PBE0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   05-JUN-2019, entry version 12.
DE   RecName: Full=Hyaluronidase {ECO:0000256|RuleBase:RU610713};
DE            EC=3.2.1.35 {ECO:0000256|RuleBase:RU610713};
DE   AltName: Full=Hyaluronoglucosaminidase {ECO:0000256|RuleBase:RU610713};
GN   ORFNames=ACOC_LOCUS1000 {ECO:0000313|EMBL:VDM52585.1};
OS   Angiostrongylus costaricensis (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Strongylida;
OC   Metastrongyloidea; Angiostrongylidae; Angiostrongylus.
OX   NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0000099901-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0000099901-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RG   Helminth Genomes Consortium;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|WBParaSite:ACOC_0000099901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:VDM52585.1, ECO:0000313|Proteomes:UP000267027}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Costa Rica {ECO:0000313|EMBL:VDM52585.1,
RC   ECO:0000313|Proteomes:UP000267027};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Random hydrolysis of (1->4)-linkages between N-acetyl-
CC         beta-D-glucosamine and D-glucuronate residues in hyaluronate.;
CC         EC=3.2.1.35; Evidence={ECO:0000256|RuleBase:RU610713};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 56 family.
CC       {ECO:0000256|RuleBase:RU610713}.
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DR   EMBL; UYYA01000128; VDM52585.1; -; Genomic_DNA.
DR   WBParaSite; ACOC_0000099901-mRNA-1; ACOC_0000099901-mRNA-1; ACOC_0000099901.
DR   Proteomes; UP000050601; Genome assembly.
DR   Proteomes; UP000267027; Unassembled WGS sequence.
DR   GO; GO:0004415; F:hyalurononglucosaminidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR018155; Hyaluronidase.
DR   PANTHER; PTHR11769; PTHR11769; 1.
DR   Pfam; PF01630; Glyco_hydro_56; 1.
DR   PRINTS; PR00846; GLHYDRLASE56.
DR   SUPFAM; SSF51445; SSF51445; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000050601,
KW   ECO:0000313|Proteomes:UP000267027};
KW   Glycosidase {ECO:0000256|RuleBase:RU610713};
KW   Hydrolase {ECO:0000256|RuleBase:RU610713};
KW   Reference proteome {ECO:0000313|Proteomes:UP000267027};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    175       Hyaluronidase. {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5018920721.
SQ   SEQUENCE   175 AA;  20384 MW;  3AF27A140F909D81 CRC64;
     MLTALTVFVI LFDSVLSQLD SFPVYWNVPS KVCYDREVEI PLQQFGIKHN IGHEFLGDQI
     VIFYEYDFGY FPYFNNGDVN EPVNGGLPQN CSIDKHLARV SEQIRAAIPR EDFSGIAVID
     FEEWRPLYKL NWGKKSVYKM ESIRLVRQQY PSISNKSAEE MARKEFEAAA KYDFF
//
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