ID   A0A0R3PCG0_ANGCS        Unreviewed;       272 AA.
AC   A0A0R3PCG0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Hist_deacetyl domain-containing protein {ECO:0000313|WBParaSite:ACOC_0000149701-mRNA-1};
GN   ORFNames=ACOC_LOCUS1498 {ECO:0000313|EMBL:VDM53083.1};
OS   Angiostrongylus costaricensis (Nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC   Angiostrongylus.
OX   NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0000149701-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ACOC_0000149701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDM53083.1, ECO:0000313|Proteomes:UP000267027}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Costa Rica {ECO:0000313|EMBL:VDM53083.1,
RC   ECO:0000313|Proteomes:UP000267027};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + N(6)-acetyl-L-lysyl-[histone] = acetate + L-lysyl-
CC         [histone]; Xref=Rhea:RHEA:58196, Rhea:RHEA-COMP:9845, Rhea:RHEA-
CC         COMP:11338, ChEBI:CHEBI:15377, ChEBI:CHEBI:29969, ChEBI:CHEBI:30089,
CC         ChEBI:CHEBI:61930; EC=3.5.1.98;
CC         Evidence={ECO:0000256|ARBA:ARBA00001028};
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DR   EMBL; UYYA01000225; VDM53083.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R3PCG0; -.
DR   STRING; 334426.A0A0R3PCG0; -.
DR   WBParaSite; ACOC_0000149701-mRNA-1; ACOC_0000149701-mRNA-1; ACOC_0000149701.
DR   OMA; CRCWLVA; -.
DR   Proteomes; UP000050601; Unplaced.
DR   Proteomes; UP000267027; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000267027}.
FT   DOMAIN          2..258
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
SQ   SEQUENCE   272 AA;  30637 MW;  39A038DD2438615E CRC64;
     MASEEEIEMV HTKDYIMKIK NTTSMVEEQL EEFSSQYEDI YVNRQTFQVA LLAAGCTLEL
     MDAVTRTGYP GFAAIRPPGH HAFPDQGCGF CIFNNVAIAA KHALKNGYSR VLIVDWDVHA
     GQGTQECIRD DDRIRLISIH RYQQGHFWPN LQQSAVKTQF KNTINVPLND IGMCDSDYLA
     IFQLIVHPVI NDFRPDVILV SCGFDAALGD PEGQMRLTPA GYATLTHQLM TWKIPLVMIL
     EGGYFMESIA AGFEWMAKSM LGDEIPRIEL KV
//