ID A0A0R3PW25_ANGCS Unreviewed; 219 AA.
AC A0A0R3PW25;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN ORFNames=ACOC_LOCUS10299 {ECO:0000313|EMBL:VDM61884.1};
OS Angiostrongylus costaricensis (Nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae;
OC Angiostrongylus.
OX NCBI_TaxID=334426 {ECO:0000313|Proteomes:UP000050601, ECO:0000313|WBParaSite:ACOC_0001029801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ACOC_0001029801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM61884.1, ECO:0000313|Proteomes:UP000267027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Costa Rica {ECO:0000313|EMBL:VDM61884.1,
RC ECO:0000313|Proteomes:UP000267027};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 1/4.
CC {ECO:0000256|ARBA:ARBA00004888}.
CC -!- SIMILARITY: Belongs to the hexokinase family.
CC {ECO:0000256|RuleBase:RU362007}.
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DR EMBL; UYYA01004444; VDM61884.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3PW25; -.
DR STRING; 334426.A0A0R3PW25; -.
DR WBParaSite; ACOC_0001029801-mRNA-1; ACOC_0001029801-mRNA-1; ACOC_0001029801.
DR OMA; MYLGDLC; -.
DR Proteomes; UP000050601; Unplaced.
DR Proteomes; UP000267027; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR Gene3D; 3.40.367.20; -; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR001312; Hexokinase.
DR InterPro; IPR022673; Hexokinase_C.
DR PANTHER; PTHR19443; HEXOKINASE; 1.
DR PANTHER; PTHR19443:SF32; PHOSPHOTRANSFERASE; 1.
DR Pfam; PF03727; Hexokinase_2; 1.
DR PRINTS; PR00475; HEXOKINASE.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR PROSITE; PS51748; HEXOKINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362007};
KW Glycolysis {ECO:0000256|RuleBase:RU362007};
KW Kinase {ECO:0000256|RuleBase:RU362007};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362007};
KW Reference proteome {ECO:0000313|Proteomes:UP000267027};
KW Transferase {ECO:0000256|RuleBase:RU362007}.
FT DOMAIN 24..213
FT /note="Hexokinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03727"
SQ SEQUENCE 219 AA; 24382 MW; BE215EA433A5E3BF CRC64;
MDLGKFHRED HTFFKIIIAD LMAKGELDSI LTQFDKEIDE ASVHKGKQII DKLTGALYLG
ELVRRILSQL VLDRVLFDGH PCEKLDETDS FPTKYISEIL AEEENSYKAC RRICDELDVP
MHGSGDYHII RDVCFVVSNR SAAIVAAAIS ALLRHLDISK VKIGVGGALI QFHPIYHKLL
EEKLTDLAPL STEWELVPAD EGSARGAALI AAVAEKMKL
//
