ID A0A0R3Q311_9BILA Unreviewed; 1400 AA.
AC A0A0R3Q311;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=UBC core domain-containing protein {ECO:0000313|WBParaSite:BTMF_0000065201-mRNA-1};
GN ORFNames=BTMF_LOCUS43 {ECO:0000313|EMBL:VDO06604.1};
OS Brugia timori.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0000065201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BTMF_0000065201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO06604.1, ECO:0000313|Proteomes:UP000280834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000256|ARBA:ARBA00008661}.
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DR EMBL; UZAG01000008; VDO06604.1; -; Genomic_DNA.
DR STRING; 42155.A0A0R3Q311; -.
DR WBParaSite; BTMF_0000065201-mRNA-1; BTMF_0000065201-mRNA-1; BTMF_0000065201.
DR Proteomes; UP000050602; Unplaced.
DR Proteomes; UP000280834; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR Gene3D; 3.90.550.50; -; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR002659; Glyco_trans_31.
DR InterPro; IPR009447; PIGW/GWT1.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR PANTHER; PTHR20661; PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN; 1.
DR PANTHER; PTHR20661:SF0; PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
DR Pfam; PF06423; GWT1; 2.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS50127; UBC_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000280834};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 121..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 568..592
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 604..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 628..651
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 754..773
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 779..799
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 806..822
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 849..872
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 879..896
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 916..944
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 970..989
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1001..1026
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1108..1127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1133..1153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1223..1241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1262..1283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1289..1305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1326..1347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1371..1388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..83
FT /note="UBC core"
FT /evidence="ECO:0000259|PROSITE:PS50127"
SQ SEQUENCE 1400 AA; 160461 MW; 8A697BCC78F55A9D CRC64;
MLTPSGRFQT NTRLCLSISD FHPDTWNPAW TVSTIITGLL SFMNDTAPTL GSITSSDAEK
RILARKSREF NLKDRIFCEL FGDLAKQIRE ELAEERNKLL SEENVIDETA SQRRSGEEGE
YATLTYNLVV LAGVVLIAFA RKAVRKLSLV DTVENSSEMA SRSFIPARIL ILFCGCLICI
ICTITLSLTC ICGEQFTSGR PRNLASSDMH KQQGVEGVSD LPSTYLAIVI MSSAGDAVLR
TVIRNTWLKL SSKGKATFRY AFPIGIENLS LIFKERLKEE NNLFNDLIFL EDLTDTYQNL
TKKSLLSMQA IHNMYKFEFL LKVDSDSFVR LGAFLKALKD IADPNLYWGF LDGRARPKRR
GQWAERDWIL CDRYVPYQLG GGYVLSYKLV DFLVRNKDLL KFYKNEDVSV GAWLAGLSVR
YVHDPRFDTE FRSRGCNNQY IVTHKQTPES LNKLYASIVN TGKLCEKEYR IHPSYVYDWS
VPPRVAFSIL ALGMRKGEWS KVELACQLFV FSSFSLEMFG KKIIMDSGRL SVTQSSGIYP
AAQTLLTNNA QIEGSNFVYN GTSQTELVLW QLIGPFSILL RNIAVPWIFV GFRFALSSGF
WLKFALDFLF IVLPVILSLT LFSDHLLLIL LFQLVALLSL ITFLLCEYCF IAREKPTLRQ
IFGQMVDDHH SPTKFITYMR SMSLIATAIA ILSVDFDIFP RRFAKTHTYG RSVMDVGTAT
SVYCFAVVDV FKDFPSRSKF PSLQRSRHFF RKHLPSIILL CLGFGRTCVL HLLSYPTQIA
EYGVHWNFFI TLAFLRITVK LLGRRFHLLF GIIVIFVYQY FLTERNLQNW LLSESVNRDT
FIAMNREGIF SLFGYLSIYY FASTIASFMY FTGIRLKSWF YRTFQLFIIA ALLFFAQKLA
EMLVGPPSRR IANLSYILEM LVFHTVYMAS LLLIQLTSIF GWAAQMPQFS IDESPFERLK
PCVLDSVNRY AMPFFLLANL LTGLINLTIT TSSVTSVYHS MTIIIVYMFI SCSVIHVCTS
VSPMLFKCSK RTIRFDNEKE YDVDEIDLVV NHTKSLFIII HSIEMRNGTT QAEVLLFQTV
GPMSIILRNI AVPGVLCIFP CTLQIGSWLT FVLDLLLIVL PVVLTLTLFS DHILLLLLAQ
TIILLTFVVV LICDQYFMKR RKRTYCDLFH QINDDHYSPT KFVTYMRLYG FLATAGAILS
VDFDVFPRRF AKTSIFGRSV MDLGTATFVY CFAVVDVFRH YPGRVKHVTQ KQWYCSLKPS
SSAVLIVLGI ARTFLLHFTN YQYQISEYGI YWNFFITLGL LRQYLISNET KRKDFVSKNR
EGIFSFFGYL SIYYLASAIA NFLFAAISHQ EYCDPNINCS ITEKRKRIKV WFYRSFQLLL
LTVVIFLAQE FAIKLVGPPS
//
