ID   A0A0R3QAK1_9BILA        Unreviewed;       305 AA.
AC   A0A0R3QAK1;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Degenerin mec-10 {ECO:0000313|WBParaSite:BTMF_0000337001-mRNA-1};
OS   Brugia timori.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0000337001-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:BTMF_0000337001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
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DR   AlphaFoldDB; A0A0R3QAK1; -.
DR   STRING; 42155.A0A0R3QAK1; -.
DR   WBParaSite; BTMF_0000337001-mRNA-1; BTMF_0000337001-mRNA-1; BTMF_0000337001.
DR   Proteomes; UP000050602; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690:SF242; DEGENERIN UNC-8; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|RuleBase:RU000679}.
SQ   SEQUENCE   305 AA;  35445 MW;  CDC4F1E7873BE4AD CRC64;
     LCFILFLYQT YWTLWEFFQY RTIIEMQLEF EPAPFPAATL CNLNAFKNSE LRKYEAISEG
     LDVWEEKINR YKGSKTSYAN NSSRKTREVS YAPVFVRCNC MQSYDHCIPE WNPLLGNATV
     CICFEDINSG NIWPCYPTVT WTEKQCFDCS LSKTCDDPDR SSFTNLRSST NGHKCLCQFV
     SNNCVIMPKD DIRWWKPNNY AILSITRSPT TSLELAEAFG LTERQDPAAM TAKAKENLIF
     MVAALSFETR RNLSYTLEEF VLRCSFNSED CNLERDFKLH MDPEYGNCYT FNFNDSVELK
     NNRAG
//