ID A0A0R3QLZ5_9BILA Unreviewed; 1216 AA.
AC A0A0R3QLZ5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Vps8 domain-containing protein {ECO:0000313|WBParaSite:BTMF_0000873001-mRNA-1};
GN ORFNames=BTMF_LOCUS6781 {ECO:0000313|EMBL:VDO22666.1};
OS Brugia timori.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0000873001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BTMF_0000873001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO22666.1, ECO:0000313|Proteomes:UP000280834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS8 family.
CC {ECO:0000256|ARBA:ARBA00009422}.
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DR EMBL; UZAG01015705; VDO22666.1; -; Genomic_DNA.
DR STRING; 42155.A0A0R3QLZ5; -.
DR WBParaSite; BTMF_0000873001-mRNA-1; BTMF_0000873001-mRNA-1; BTMF_0000873001.
DR Proteomes; UP000050602; Unplaced.
DR Proteomes; UP000280834; Unassembled WGS sequence.
DR GO; GO:0006623; P:protein targeting to vacuole; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR045111; Vps41/Vps8.
DR InterPro; IPR025941; Vps8_central_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR12616; VACUOLAR PROTEIN SORTING VPS41; 1.
DR PANTHER; PTHR12616:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF12816; Vps8; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000280834}.
FT DOMAIN 108..174
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT DOMAIN 538..715
FT /note="Vacuolar protein sorting-associated protein 8
FT central"
FT /evidence="ECO:0000259|Pfam:PF12816"
SQ SEQUENCE 1216 AA; 137386 MW; 426FBB23F3B0D54A CRC64;
MSSIATDEDI VDRWIEIDDS ISVPEQTLDE ILADKILDLD EEILCGLDDE ESLFTSPRQS
SPTSSIPSYT LDSPLHIREL ESMTYQLKTR SDSFGGRARA LAVSNANVAV GTSRGLVLIF
DCENQRLVQS MTTDGCPVSC LDFNKASTLL AIGYGSGLIR IFNVTMGKVI DNVSDVVQPG
QGVLQILFCE SDKRLACLDS GGSVYELTLP TTVRSRKTRC VFSGSHGEVV YLKLLDSDVL
ALLSLKKLFL VSLKKMCLIY AISFIGPANR PPLIDCQTVN VKKTSESMNT AFCLARGSRV
DFYYLNYEFS TLRVLHYGEL SLDFDMINLK WIESCYLIAV DDVERVHMIE TMQGDIAMEN
IRDIQLAYAT ADFKGLSTGG NVSAALDYLA DCVCYQSICR VEKMIFLLGQ SSIYMISIRD
RIMQLENLVN RGQMVSAILF ALDIVMGRVV NKREGLNLRH VVSSRIPSLI QSLLALTISG
PANGKVTQLV DHYKVSKVAV ISIEAELLIR ACVATSQFDL LYNTVYSCLE RDTLSKAIFF
DLIDEVVLDG RLENPPPALV SDYFHHLISE GNLNQFEAAV VRIPVEKQDI HFVMTTCRKN
RLYDGVIYVY NKAMSDYIGP LEEIFDNLAE LTDCEMLSDC EIALGNKLLL YIQCCLSARA
YPIGSLPEKV AATLPLQVYR CLISYKGKNG TSASITYPYL QLLIKFDAVQ FFNVIFTCSD
SDIFNSEDGR LQRITEVVYQ IIKSMDQSAV LFINYFTLVA YLLQKKAIFP ALGTINELIE
MVLSFGESVE RVADAERCVV EVMKIVNGLD EMKILRQARK LPQREFVSLM ECYLNSSTNA
RFAKIDYNQT AEIILDHFMD WLSKETLEDS DALILYYCFL ARRDRGYRTL TDSEERDEQL
LILAVKEAVV HNLFENLDTQ LSEFLRYWLT IASRTDRCLN YTVKNGFILS SVLLLEARKL
LEGAFELLEY ELEKRWMKDA MLSSKYIYEA IRLANIYHEE ARQGSWLFKI LNRILSLPES
ELQEEPGLKG VMVILNNVIT AIMESGSSDA ERLVDALFTH PVFRCSTYAN FRSLITFMFS
SCRYEDVFLK ETIRCIEGET IQIFRIRIEI SFITQLDSDK QIRRLNDLIK QATRRTAGLI
KSTMCISCGC GHMVHMDCDS ENSSHYCLCQ INAFNCCNIT NNLICGSSQV TRKPARVDIF
SEESLKLLLG PHRLES
//
