ID A0A0R3QMT2_9BILA Unreviewed; 429 AA.
AC A0A0R3QMT2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=MRG domain-containing protein {ECO:0000313|WBParaSite:BTMF_0000901701-mRNA-1};
GN ORFNames=BTMF_LOCUS7068 {ECO:0000313|EMBL:VDO23418.1};
OS Brugia timori.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0000901701-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BTMF_0000901701-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO23418.1, ECO:0000313|Proteomes:UP000280834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; UZAG01015801; VDO23418.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3QMT2; -.
DR STRING; 42155.A0A0R3QMT2; -.
DR WBParaSite; BTMF_0000901701-mRNA-1; BTMF_0000901701-mRNA-1; BTMF_0000901701.
DR Proteomes; UP000050602; Unplaced.
DR Proteomes; UP000280834; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.10.274.30; MRG domain; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR008676; MRG.
DR InterPro; IPR038217; MRG_C_sf.
DR InterPro; IPR026541; MRG_dom.
DR InterPro; IPR025995; Tudor-knot.
DR PANTHER; PTHR10880; MORTALITY FACTOR 4-LIKE PROTEIN; 1.
DR PANTHER; PTHR10880:SF48; MRG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05712; MRG; 1.
DR Pfam; PF11717; Tudor-knot; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR PROSITE; PS51640; MRG; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000280834};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..115
FT /note="Tudor-knot"
FT /evidence="ECO:0000259|Pfam:PF11717"
FT DOMAIN 204..416
FT /note="MRG"
FT /evidence="ECO:0000259|Pfam:PF05712"
FT REGION 136..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..164
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 429 AA; 49313 MW; 7E93B3614ABEBCE2 CRC64;
MKEVEICLYT AFSRTDFNKE LLGFIGGFFF CVILPSRSLK MPPKKESAAT KDAAKEVPKP
SDVYELHAKV LCQHLDNLYY EAKIINVEHG LDGEPIYTVH YQGWNQRHDE KIKHSSTRSR
FLEYTTANVE RAKAEMRDAQ ARLAQNKRRS RKSNVLDEKR SGGADSRGST PSDKRGTSTS
RAASIVSDKG TVRKRKPGTQ LESEPVSDFI RKNEIKIDIP SVLKDILVDD HDMINRQMYL
PRLPARHTVA GIVRQYADYM GTCVEAKDTL TFEFGSDDTQ LNSMVVTLVE SSYGIQDYFN
SSLGLQLLYK FERPQYADLL AQHKDKQEGT KDAKKKRSND AADGDDSPTD DYDKFKPSEY
YGFIHLLRLF VRFGHMLGLT NWSERTIETI VNQVHNFLKF LEVNRHKFFD IETDYEVAPP
EYQRRVWSS
//
