ID   A0A0R3QMT8_9BILA        Unreviewed;       952 AA.
AC   A0A0R3QMT8;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=SSD domain-containing protein {ECO:0000313|WBParaSite:BTMF_0000902301-mRNA-1};
GN   ORFNames=BTMF_LOCUS7074 {ECO:0000313|EMBL:VDO23438.1};
OS   Brugia timori.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0000902301-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:BTMF_0000902301-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO23438.1, ECO:0000313|Proteomes:UP000280834}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   EMBL; UZAG01015804; VDO23438.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0R3QMT8; -.
DR   WBParaSite; BTMF_0000902301-mRNA-1; BTMF_0000902301-mRNA-1; BTMF_0000902301.
DR   Proteomes; UP000050602; Unplaced.
DR   Proteomes; UP000280834; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF193; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000280834};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        281..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        319..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        348..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        388..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        421..446
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        591..612
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        785..811
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        818..838
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        844..869
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        890..913
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        919..943
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          287..446
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   952 AA;  108458 MW;  30195B413FB2EA33 CRC64;
     MRITSVEPEL RRFFQWYGEF GYQWRWFLIM SPLIITALLS LGFCRLTALT IDDPFYVFTP
     VYARWHQEFD TFASLWPLNE NKFLPGKSFE MKRFINVLVK AKDGGNLLRE EILDEIQGLN
     QWIMFNISIP TTDGKYNLTY QDLCLSYEWI CGTNEHISML QERMKVGNFV ELTYPRAGSK
     VSLSLILMNN EIKFSDTPVY LGTVLSDVTL NESNGTIKAA KLTQLFYFLK QEAHIVRRYS
     TAFSYAVEHY LLHNYKSDII SLSFSHYHSL QDGLAENAKD FTWNFLTSFS LLCIYATIFS
     YVLKKHPRTS IDWVRSKPYV ACAGLITTLL AMCSGFGLAL MLNIPYNVIN TIIPFLIIAI
     GVDDMFVMNA CWNQTDQTDT VSKRMSNMMA HAGVTISITN ITDILSFAVG CHSELPGIQF
     FCSYACITFI FCYLYQFTFF MAFLAIMGSV EMNQRHCLLF YKADEKCVKK EMINSARFCN
     SRNDYDNSLQ CSSTDSGSDI SYRSGISTQS NGSSLKTAIK TLSLIIAVDE LSNQKSTEMV
     DTDNNCITEG LCITTISQLK TQPIEKKKNT WTQYFFGHIY AQFILRKECA ILTYIFYFIY
     IAVAVIGCLN YSEGLEPENL VTNNHYTSHY FADLKNFWVR GTQLHVAVLH PPNLTDPIQR
     EKMMAVVQAF ENTEYTLGRD GTIFFFLEYL NYLDEVNAEL ENTERIWNTK LLSWLKYTGG
     SNQWATDIHF NENGTFQAFR FQVAMQNTVS ANQHKNAAQK LREIADRQPF KIEVFHETFP
     FADQYIIIVP STIRSIIISL ICMATVAVTL VPSLAPCALI IISIISINTG IFGYMTFWGV
     HLDAVSMISI IMSIGFAVDL SSHITYAFVM ATGSSRERVI HALESLGWPI FQGAASTIAG
     VSVLYTVNAY IILTFFKTIW LTMVIGLLHG LLFIPITLSF FPLSPFLCSK KL
//