ID A0A0R3QP38_9BILA Unreviewed; 530 AA.
AC A0A0R3QP38;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Iron-sulfur cluster assembly 1 homolog, mitochondrial {ECO:0000256|ARBA:ARBA00039743};
OS Brugia timori.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0000947301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BTMF_0000947301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SIMILARITY: Belongs to the HesB/IscA family.
CC {ECO:0000256|ARBA:ARBA00006718}.
CC -!- SIMILARITY: Belongs to the SMN family. {ECO:0000256|ARBA:ARBA00005371}.
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DR AlphaFoldDB; A0A0R3QP38; -.
DR STRING; 42155.A0A0R3QP38; -.
DR WBParaSite; BTMF_0000947301-mRNA-1; BTMF_0000947301-mRNA-1; BTMF_0000947301.
DR Proteomes; UP000050602; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.60.300.12; HesB-like domain; 1.
DR InterPro; IPR000361; FeS_biogenesis.
DR InterPro; IPR016092; FeS_cluster_insertion.
DR InterPro; IPR017870; FeS_cluster_insertion_CS.
DR InterPro; IPR035903; HesB-like_dom_sf.
DR InterPro; IPR010304; SMN_Tudor.
DR InterPro; IPR002999; Tudor.
DR NCBIfam; TIGR00049; iron-sulfur cluster assembly accessory protein; 1.
DR PANTHER; PTHR10072:SF41; IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL; 1.
DR PANTHER; PTHR10072; IRON-SULFUR CLUSTER ASSEMBLY PROTEIN; 1.
DR Pfam; PF01521; Fe-S_biosyn; 1.
DR Pfam; PF06003; SMN_Tudor; 1.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF89360; HesB-like domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS01152; HESB; 1.
DR PROSITE; PS50304; TUDOR; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187}.
FT DOMAIN 344..402
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 74..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 290..328
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 74..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 60973 MW; 23A0EAA59F71F439 CRC64;
LISIFFQRLP QSCLPVNATN EMFRANDIIS GLNKKMVDER GDDFSAARKA QIDHVIENNA
IKKFARSQLK PKPLENCAST SCNNNSKKDP VIKGKPDTEN MDRRSVRDDK KNLLPVHRPS
NPPTLYDFMQ SKVPMPDGIS TGYQNFGNLQ FPMEKIETNQ QNVETQGMDR PRRGRFNERG
FRYQQTDDNT NGSHIFEISN SNRYRKQCNW RLEREKNYAT NMVNDKVRVN HADDQLVSTA
NKELSALHLS SIDNGPLGVG KAHDVPQEIV CFENKNHGYQ QNAVHGPVYK QQQQQQRQQQ
RQQYQQHQQQ YQQQYQQQQQ RQKQQQQQQQ SFDNRMMNGG MLPVWKIGDK CLAPWSDGQF
YPSTLVSMGP ADMCTIEYDE YGNRSSVPVG RPVWIYMKLM ISRHASTAAR VIKGAIRRDM
PSKIALWLTP EAVKRVKYLL SKQPETTALK ISVRQRGCNG LTYTLDYAQQ KAKFDEEVVQ
DGVRLWIDPK AQLSLLGSEM DYVEDRLSSE FVFRNPNIKG TCGCGESFSI
//
