ID A0A0R3QR69_9BILA Unreviewed; 751 AA.
AC A0A0R3QR69;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=G_PROTEIN_RECEP_F3_4 domain-containing protein {ECO:0000313|WBParaSite:BTMF_0001020401-mRNA-1};
GN ORFNames=BTMF_LOCUS8255 {ECO:0000313|EMBL:VDO27469.1};
OS Brugia timori.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0001020401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BTMF_0001020401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO27469.1, ECO:0000313|Proteomes:UP000280834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UZAG01016311; VDO27469.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3QR69; -.
DR STRING; 42155.A0A0R3QR69; -.
DR WBParaSite; BTMF_0001020401-mRNA-1; BTMF_0001020401-mRNA-1; BTMF_0001020401.
DR Proteomes; UP000050602; Unplaced.
DR Proteomes; UP000280834; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR000162; GPCR_3_mtglu_rcpt.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR24060:SF158; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR00593; MTABOTROPICR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000280834};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 409..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 598..620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 626..650
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 410..672
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 751 AA; 86718 MW; DCF0E7C18208FF63 CRC64;
MIDIALHFNW TYVSLVYSAD EYGELGAEAF KKEARKMNIC IAIEERISPK KEAFQESVDN
LVKKLQPDKV VGARAVVLFV ATEYVPELML QTFERMRFER LPRRKDIIWL ASEGWDRNNE
AYTAGPRKSV AEGAIVLMLA SDRVPSFEEY FLSLNPSHNK FERNKWLREL WRHKFNCEFD
LPERSTLNKC ENHYQTMENF NPDDKVQFVI DAVYAIAHGL QGMQEKVCPD DTASSSWISR
YSSVPQICDA MKHIDGEEFY QKYLLQVKFE GNILRSYSHA VGKKFRFSPE GDGPAHYTIL
NYQPEIGHSR SEDSSRSDYV VVGRWSEDQL DIDDEKMSWK YGEIPISQCS MPCPDEICCW
ACSKCEDYEF LPDETTCVDC GEGWWPTTDR KNCFNLAQSS LKYIRWSSWY SIIPTLFAVV
GICSTIAAIV IYSRNHDTPV VKASGRELSY IILLAMIMCY TMTFLLISRP TTFNCAIKRT
GIGFAFSCLY AALLVKTNRI ARIFSHRSVQ RPMCISPVSQ VLLTALLAGL QLFGSLIWLF
IVPPGTKHYY PTRDQVVLKC NVPDHHFLYS LAYDAALIVL CTVYAIKTRK VPENFNETRF
IGFTMYTTCV LWLSWIFFFF GTGSDFQIQT TSLCISISMS ANVALACIFL PKIWIILFEK
HKNAHRQDGI FTKRVPLVRA IAPVNRCFML AGMFHLPVID RSNSESYDNK YIRERSTYTM
YCLVIRATEE KFTRKLLLQH LIFRSRHIFV K
//
