ID A0A0R3R8C9_9BILA Unreviewed; 94 AA.
AC A0A0R3R8C9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Stress-associated endoplasmic reticulum protein {ECO:0000313|WBParaSite:BTMF_0001628501-mRNA-1};
GN ORFNames=BTMF_LOCUS14266 {ECO:0000313|EMBL:VDO48675.1};
OS Brugia timori.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=42155 {ECO:0000313|Proteomes:UP000050602, ECO:0000313|WBParaSite:BTMF_0001628501-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:BTMF_0001628501-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO48675.1, ECO:0000313|Proteomes:UP000280834}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Interacts with target proteins during their translocation
CC into the lumen of the endoplasmic reticulum. Protects unfolded target
CC proteins against degradation during ER stress. May facilitate
CC glycosylation of target proteins after termination of ER stress. May
CC modulate the use of N-glycosylation sites on target proteins.
CC {ECO:0000256|ARBA:ARBA00037157}.
CC -!- SUBUNIT: Interacts with SEC61B, SEC61A1 and the SEC61 complex.
CC Interacts with CANX. {ECO:0000256|ARBA:ARBA00038831}.
CC -!- SIMILARITY: Belongs to the RAMP4 family.
CC {ECO:0000256|ARBA:ARBA00005500}.
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DR EMBL; UZAG01021001; VDO48675.1; -; Genomic_DNA.
DR STRING; 42155.A0A0R3R8C9; -.
DR WBParaSite; BTMF_0001628501-mRNA-1; BTMF_0001628501-mRNA-1; BTMF_0001628501.
DR Proteomes; UP000050602; Unplaced.
DR Proteomes; UP000280834; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR010580; ER_stress-assoc.
DR PANTHER; PTHR15601:SF0; GEO09675P1; 1.
DR PANTHER; PTHR15601; STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4; 1.
DR Pfam; PF06624; RAMP4; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000280834};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Unfolded protein response {ECO:0000256|ARBA:ARBA00023230}.
SQ SEQUENCE 94 AA; 10556 MW; 3D82D0930FA152BA CRC64;
MFLRSCIIRL KSLDLIHLAL SNNLADLLVS RKSVQMPAKQ RMSVANSVFS RNVLSRGNVQ
KTLKPQEDKY STTPWLIGLF VFVVCGSGKI LSIY
//
