ID A0A0R3RFA6_9BILA Unreviewed; 71 AA.
AC A0A0R3RFA6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=General transcription and DNA repair factor IIH subunit TFB5 {ECO:0000256|RuleBase:RU368032};
OS Elaeophora elaphi.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Elaeophora.
OX NCBI_TaxID=1147741 {ECO:0000313|Proteomes:UP000050640, ECO:0000313|WBParaSite:EEL_0000003201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EEL_0000003201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- FUNCTION: In NER, TFIIH acts by opening DNA around the lesion to allow
CC the excision of the damaged oligonucleotide and its replacement by a
CC new DNA fragment. In transcription, TFIIH has an essential role in
CC transcription initiation. When the pre-initiation complex (PIC) has
CC been established, TFIIH is required for promoter opening and promoter
CC escape. {ECO:0000256|RuleBase:RU368032}.
CC -!- SUBUNIT: Component of the 7-subunit TFIIH core complex.
CC {ECO:0000256|RuleBase:RU368032}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU368032}.
CC -!- SIMILARITY: Belongs to the TFB5 family. {ECO:0000256|ARBA:ARBA00007470,
CC ECO:0000256|RuleBase:RU368032}.
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DR AlphaFoldDB; A0A0R3RFA6; -.
DR STRING; 1147741.A0A0R3RFA6; -.
DR WBParaSite; EEL_0000003201-mRNA-1; EEL_0000003201-mRNA-1; EEL_0000003201.
DR Proteomes; UP000050640; Unplaced.
DR GO; GO:0000439; C:transcription factor TFIIH core complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005675; C:transcription factor TFIIH holo complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.1220; TFB5-like; 1.
DR InterPro; IPR035935; TFB5-like_sf.
DR InterPro; IPR009400; TFIIH_TTDA/Tfb5.
DR PANTHER; PTHR28580; GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5; 1.
DR PANTHER; PTHR28580:SF1; GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5; 1.
DR Pfam; PF06331; Tfb5; 1.
DR SMART; SM01395; Tbf5; 1.
DR SUPFAM; SSF142897; TFB5-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU368032};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU368032};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU368032};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU368032};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU368032}.
SQ SEQUENCE 71 AA; 8149 MW; 21E94FC3B66BEB4B CRC64;
MVNVKKGVLV RCDPAMRQLL VYLDESRTLG SKFVVKELDE THVIVDKEIV PILEQKLDQM
MESLSPDFSD K
//