ID   A0A0R3RJ41_9BILA        Unreviewed;       403 AA.
AC   A0A0R3RJ41;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=A_deaminase domain-containing protein {ECO:0000313|WBParaSite:EEL_0000149901-mRNA-1};
OS   Elaeophora elaphi.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Elaeophora.
OX   NCBI_TaxID=1147741 {ECO:0000313|Proteomes:UP000050640, ECO:0000313|WBParaSite:EEL_0000149901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EEL_0000149901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + H2O + N(6)-methyl-AMP = IMP + methylamine;
CC         Xref=Rhea:RHEA:16001, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:58053, ChEBI:CHEBI:59338, ChEBI:CHEBI:144842;
CC         Evidence={ECO:0000256|ARBA:ARBA00036622};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16002;
CC         Evidence={ECO:0000256|ARBA:ARBA00036622};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A0R3RJ41; -.
DR   STRING; 1147741.A0A0R3RJ41; -.
DR   WBParaSite; EEL_0000149901-mRNA-1; EEL_0000149901-mRNA-1; EEL_0000149901.
DR   Proteomes; UP000050640; Unplaced.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF42; ADENOSINE DEAMINASE-LIKE PROTEIN; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
FT   DOMAIN          47..363
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   403 AA;  46514 MW;  ACD01CC51168FAE5 CRC64;
     MEKVSAQDTQ IIHHPNHETP RTYLLDNRNA KNTNDVQPVQ IFCHQMPKCE FHAHLTGSIS
     RKMLHTLDLR HRSDYGIDLI QDELSRLHEY DRKPRNLVEA FELFPLIQQL VVEPEDVAEV
     TSEVIREFSE ENVVYLELRS TPRQTTRMSK EEYVKALITG VVQSRQLYSS ICVRLLLSID
     RRQTVEEASE TVKLALRYGK HNDDKAINGI IVGVEVSGDP KYDARKFLPL LREAKNDLPV
     ITFHLAEMEE YMDEVEECVF FGPTRIGHAT FLHKISDEAQ LNKISEYLCK NRIPIEICLS
     SNMVCGTVKS VEASHLAHYF EKKHPILIST DDRAMMCCSL SDEYEHVARA LNLDAQEIFN
     LSYSTTKYIC KNLTAGEKLL IFNQFHKFAK TQNLTLKYSK IQP
//