ID   A0A0R3RSB1_9BILA        Unreviewed;       596 AA.
AC   A0A0R3RSB1;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=Transmembrane emp24 domain-containing protein eca {ECO:0000256|ARBA:ARBA00040830};
OS   Elaeophora elaphi.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Elaeophora.
OX   NCBI_TaxID=1147741 {ECO:0000313|Proteomes:UP000050640, ECO:0000313|WBParaSite:EEL_0000469401-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:EEL_0000469401-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC       pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC   -!- SIMILARITY: Belongs to the EMP24/GP25L family.
CC       {ECO:0000256|ARBA:ARBA00007104}.
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DR   AlphaFoldDB; A0A0R3RSB1; -.
DR   STRING; 1147741.A0A0R3RSB1; -.
DR   WBParaSite; EEL_0000469401-mRNA-1; EEL_0000469401-mRNA-1; EEL_0000469401.
DR   Proteomes; UP000050640; Unplaced.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR015720; Emp24-like.
DR   InterPro; IPR009038; GOLD_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR22811; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR22811:SF159; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 4; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   Pfam; PF01105; EMP24_GP25L; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SMART; SM01190; EMP24_GP25L; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS50866; GOLD; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..596
FT                   /note="Transmembrane emp24 domain-containing protein eca"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5006447754"
FT   DOMAIN          27..122
FT                   /note="GOLD"
FT                   /evidence="ECO:0000259|PROSITE:PS50866"
FT   COILED          131..158
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   596 AA;  68919 MW;  318F1BED868D44FF CRC64;
     MLIVVLFLTL LCSSVRALYF HIAETERKCF IEEIPDETTV IGNYKVMLYD PNTKGYGEYP
     RIGMHVEVKD PEDKIILSKL YTSEGRFTFT SHSPGEHFIC LYSNSSSWFS GAQLRVYLDI
     QTGEHTQDYE QVAAKDKLNE LQLRVRQLLD QVEQISKEQN YQRYREERFR QTSENTNSRV
     LWWSIAQTIV LLLTGAWQMR HLKGFFEAKK LENVYSKKGE NKIIERMAGG NCCRCSILNV
     NLLNFSHGEP YDNYKFEHDL TNKTYIVVGA SSGIGKETAK ELAMRKAKVI MACRDNRKCI
     EARRNMVIST KNMDIYCRRL NLEDFDSIRD FVLKLDTGKG NIDRIDGIVY SAATVESTRR
     TNKHHIERTF ATNHLGPFLL TSLLYDRLRK QSSPVRLVFL NTSDLKLDEL NFDGLNSTDL
     TKWQKSPEKA KKDAYYQSKL ALTLFVKLLS EKVKGTNLRV TMVDPGDTKT DLFYRLGAAD
     GRVFFVRWCK SLKRWIYGLL VAQSISDATR PVLYALADEK MENVNGIFIN SVRDELPWHK
     LASDEKILNK LWLTSAKWTE TGVHLQRLQQ DLKKPKSQET GATQELKART GWFSWL
//