ID A0A0R3RUW3_9BILA Unreviewed; 541 AA.
AC A0A0R3RUW3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=E2F_TDP domain-containing protein {ECO:0000313|WBParaSite:EEL_0000583901-mRNA-1};
OS Elaeophora elaphi.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Elaeophora.
OX NCBI_TaxID=1147741 {ECO:0000313|Proteomes:UP000050640, ECO:0000313|WBParaSite:EEL_0000583901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:EEL_0000583901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
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DR AlphaFoldDB; A0A0R3RUW3; -.
DR STRING; 1147741.A0A0R3RUW3; -.
DR WBParaSite; EEL_0000583901-mRNA-1; EEL_0000583901-mRNA-1; EEL_0000583901.
DR Proteomes; UP000050640; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd14660; E2F_DD; 1.
DR Gene3D; 6.10.250.540; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR015633; E2F.
DR InterPro; IPR037241; E2F-DP_heterodim.
DR InterPro; IPR032198; E2F_CC-MB.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12081; TRANSCRIPTION FACTOR E2F; 1.
DR PANTHER; PTHR12081:SF18; TRANSCRIPTION FACTOR E2F2; 1.
DR Pfam; PF16421; E2F_CC-MB; 1.
DR Pfam; PF02319; E2F_TDP; 1.
DR SMART; SM01372; E2F_TDP; 1.
DR SUPFAM; SSF144074; E2F-DP heterodimerization region; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|RuleBase:RU003796};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 230..296
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT REGION 41..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 310..337
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 139..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 59930 MW; 9AC1AEC33B7925AC CRC64;
MAAASSTQPS LYQHYFTGHL SNNSSITVNH RAGLNSEAKS AAWSSPVAGQ QLDEDSGMSV
RNGRTEDGSW TTDLAATSFM PSSTNGQNSC GSVNNYGGWN TDYVSNSDRY ISQNTSQQMI
PATPKGRKPE LATAPSARNS EPHIANPRFT DSQGSSTSQA LLQSECESHS RPTSSRKRHA
DSYQCKPSFT SSYLRTSEQL RKNLLPCSYP MSMSTCETLS AAQFGPLNCR VDNSLLVLTK
KFMQLQPQAN EDGLLNLNEA AMRLGVQKRR LYDITNVLEG IDMIEKMGKN SIRWKSNDEI
GSRGIEAQRL KEEIKSLDKY EQSLDELITS IENALKLAKE DPTDRVYSYV KYADLRMLPG
MSDQTLIAIK APKDSYSSID VTDPVETGKF EIMIRNAQKE SLEAYLCPHV SPKNQQFQKE
EPCDALAQED RSNWSEQATN DVFQEINRDA QVSIPGPSND NNVNILPINA LSSFYAPQTL
HTSPLKMVVE GPSQQAVSSS NTEDTTSNSY GLLSLDPVDE SEPYMYSIGE QESIQTLYDW
P
//
