ID A0A0R3S7X2_HYMDI Unreviewed; 906 AA.
AC A0A0R3S7X2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Glutamate receptor {ECO:0000313|WBParaSite:HDID_0000018301-mRNA-1};
GN ORFNames=HDID_LOCUS184 {ECO:0000313|EMBL:VDL13937.1}, WMSIL1_LOCUS3214
GN {ECO:0000313|EMBL:VUZ42581.1};
OS Hymenolepis diminuta (Rat tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX NCBI_TaxID=6216 {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0000018301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HDID_0000018301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL13937.1, ECO:0000313|Proteomes:UP000274504}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:VUZ42581.1, ECO:0000313|Proteomes:UP000321570}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WMS-il1 {ECO:0000313|EMBL:VUZ42581.1,
RC ECO:0000313|Proteomes:UP000321570};
RA Jastrzebski P J., Paukszto L., Jastrzebski P J.;
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; UYSG01000018; VDL13937.1; -; Genomic_DNA.
DR EMBL; CABIJS010000089; VUZ42581.1; -; Genomic_DNA.
DR STRING; 6216.A0A0R3S7X2; -.
DR WBParaSite; HDID_0000018301-mRNA-1; HDID_0000018301-mRNA-1; HDID_0000018301.
DR Proteomes; UP000046397; Unplaced.
DR Proteomes; UP000274504; Unassembled WGS sequence.
DR Proteomes; UP000321570; Unassembled WGS sequence.
DR GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR001508; Iono_Glu_rcpt_met.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966:SF422; KAINATE-TYPE IONOTROPIC GLUTAMATE RECEPTOR SUBUNIT 1D; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR PRINTS; PR00177; NMDARECEPTOR.
DR SMART; SM00918; Lig_chan-Glu_bd; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00023257};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000274504};
KW Signal {ECO:0000256|SAM:SignalP}; Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..906
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040566388"
FT TRANSMEM 874..896
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 482..851
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DOMAIN 492..559
FT /note="Ionotropic glutamate receptor L-glutamate and
FT glycine-binding"
FT /evidence="ECO:0000259|SMART:SM00918"
SQ SEQUENCE 906 AA; 102071 MW; 4B2DAACBF9DB4356 CRC64;
MLFTKSSLLA LLVFFPPFIN SAENNSRGVT IILDTPTGNI TASGGKSQLV GVIRRLAQRY
RESPAIQRIQ ENRGYTVLSG YCRALAVERA ALIGILPSPV APLFQSLSST FGYPYITWDE
IPPIFEHPLG NLVDSGCKLF SVRPDITQPL IDYITTWQWN SFAYLYGSMD AFKRLQFINQ
KITDLDILPG SSIPRPPSGK PAFKTQPPIV SGHIDVNDDE VMHSTLKSID AYLSLKSERN
VIIDMGKPKN SLSLSGIKRL NTLITWFRRM GMMRSEYSYL LVDFDIYELN LDEYRQSGVT
FRGFHFLDYQ NDVVVKFAAE WKDAQTPLHT IASIMDALEV GRSLKKVVDN GLWKGRDSTI
KSKCFTSSGT LVSDSFIQRW QPGPRVKSWL TTTEIIGQTG LIKFDEGTCQ RTDYNLLLST
VFGEKRKRTI AKWSRHSGWV LPSMSTNLGF SNRMPYAGLR ERMSEPITYN NLLEIYRLRN
KTLRVVTVLS KPFIMPASPE VSDAKAGRDN FVGYCKDLAD YIFSELNLNY EMHLVKDNKF
GVIDPDTGEW NGMVGEILRD EADLIIAPLT MNTMRAKVID FSEPFMNFGL ALIIRKPGKT
KPGMFSFLSP LKNEVWLRMA AATIIVSLGL RLIAAISPKE RKPANPALGF NLGNCIWFSV
ASFVHQGIDI FPISPGARVF ASIWRYVCLV VMAYYTANLA AALSVERLIS PINSIKDFAE
KKDLPIQIGT LDSGATKDFF THAKDNLYRT IFKRMEKDPS VYVPTLEAGF ERVRTKSYTF
VAESKMIEYI NHRQPCDTMM VGSVFGSKAY AVGLPSNKPE MRIFKEHVTD VILRLRENQV
LAKLYKEWWI EKGECLQGGE QQSSEPLALI NLSGVFYILI GGMILAMMVG AIVFFLKVRK
LDSAKK
//
