ID A0A0R3SAT7_HYMDI Unreviewed; 953 AA.
AC A0A0R3SAT7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=HDID_LOCUS1501 {ECO:0000313|EMBL:VDL18962.1};
OS Hymenolepis diminuta (Rat tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX NCBI_TaxID=6216 {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0000150001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HDID_0000150001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL18962.1, ECO:0000313|Proteomes:UP000274504}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; UYSG01000280; VDL18962.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3SAT7; -.
DR STRING; 6216.A0A0R3SAT7; -.
DR WBParaSite; HDID_0000150001-mRNA-1; HDID_0000150001-mRNA-1; HDID_0000150001.
DR Proteomes; UP000046397; Unplaced.
DR Proteomes; UP000274504; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 3.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR20875; EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR20875:SF5; EF-HAND DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR SUPFAM; SSF47473; EF-hand; 2.
DR SUPFAM; SSF48652; Tetraspanin; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000274504};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 411..446
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 953 AA; 110959 MW; 3FE007A574158F03 CRC64;
MKSSKVLWII TILWTLLYAI AFLSTSLMVY VKRKHVQLVL DEKTMIITVS VTGTYAGWLF
ICIGTALQVI RSKKRGVALI FLVLVLISLV FELYFLTFVF TRRSEFLRDS FTMIIKGLVE
NYTKSNVSKV YTDWINEEFQ CCGLTQWHRE WWMDEGGFLK KEFKFAWVPD SCCLENSRYN
NCGIAYPPRK PGVTEEDKSV TDIRQFYYES GALAATYWYM RLKNEPCPDM MTERLDEISI
YILMTSITLS FTRFTISLGA VIGFLVAFAF ENILLGARSK EFNLRELLPP SCFDPNGRIL
KPQFREMLAR MNIQLTDENF RRLWEQKFDL DGIGSISTKQ LIDQLNLSEQ GVPKDESTKP
VNRKFPDSHR LKYEACYEYK PILKENSCRP LVLEPITKPL IMKKEDDKFR SPLVALNNVL
KRGDTDNKGS ISFAYLLAVI KDLGIKVSAE DVKKYCRRRG LFVDMNKGAC DMTGNDIFYG
KLLMQLKCNQ PHRAIANLSH DPCKLNGHRK TRYLEDEIYN IIFADNLDFI AKLKKYDSQG
GDPLPQFREL IDSTIGFEMG DCSWKELVRQ VRLINDCRVD INHLISSVFE TCKPSSDEES
NADKMLLDPQ LRDLVVFTGE PRSLSQLLLA LKKLITEQFH VIDKLYKHME HKGFATIDKK
DFGTVMKKVG LEFCSEELDA LWQLLEEVEP TSDGIHKYHQ VMRFFLESEP IRTELSTEKR
HKRIHDPNLP KMKEFYQCQK DIKKQNTEQI LALGKAASEI KYKKREDEKL SEERINELCS
KIRPFVISIW TNLRNGFLYQ DPLGWGTMLR KEFRNICAAF DLPLNENELT ELARGLDRKN
DGFVNYVDFL KRFSDGHTPP KICQKFDFIH YKLKNKCLKE YKTMSAGFRA IADSKHPEFF
TEENLGKFLR KHGFDFSADD IYHIRTAYDT RRRGCISYTD FLQQTMDVIK PAE
//
