ID A0A0R3SVZ5_HYMDI Unreviewed; 588 AA.
AC A0A0R3SVZ5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Proteasome subunit alpha type-1 {ECO:0000256|ARBA:ARBA00021331};
GN ORFNames=HDID_LOCUS9787 {ECO:0000313|EMBL:VDL62206.1};
OS Hymenolepis diminuta (Rat tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Hymenolepididae; Hymenolepis.
OX NCBI_TaxID=6216 {ECO:0000313|Proteomes:UP000046397, ECO:0000313|WBParaSite:HDID_0000978901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:HDID_0000978901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL62206.1, ECO:0000313|Proteomes:UP000274504}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin C subfamily.
CC {ECO:0000256|ARBA:ARBA00008638}.
CC -!- SIMILARITY: Belongs to the peptidase T1A family. {ECO:0000256|PROSITE-
CC ProRule:PRU00808}.
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DR EMBL; UYSG01011396; VDL62206.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3SVZ5; -.
DR STRING; 6216.A0A0R3SVZ5; -.
DR WBParaSite; HDID_0000978901-mRNA-1; HDID_0000978901-mRNA-1; HDID_0000978901.
DR Proteomes; UP000046397; Unplaced.
DR Proteomes; UP000274504; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd20524; CYCLIN_CCNH_rpt1; 1.
DR CDD; cd20525; CYCLIN_CCNH_rpt2; 1.
DR CDD; cd03749; proteasome_alpha_type_1; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR031658; Cyclin_C_2.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR InterPro; IPR023332; Proteasome_alpha-type.
DR InterPro; IPR035144; Proteasome_alpha1.
DR InterPro; IPR000426; Proteasome_asu_N.
DR InterPro; IPR001353; Proteasome_sua/b.
DR PANTHER; PTHR11599:SF12; PROTEASOME SUBUNIT ALPHA TYPE-1; 1.
DR PANTHER; PTHR11599; PROTEASOME SUBUNIT ALPHA/BETA; 1.
DR Pfam; PF16899; Cyclin_C_2; 1.
DR Pfam; PF00227; Proteasome; 1.
DR Pfam; PF10584; Proteasome_A_N; 1.
DR SMART; SM00948; Proteasome_A_N; 1.
DR SUPFAM; SSF47954; Cyclin-like; 2.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR PROSITE; PS00388; PROTEASOME_ALPHA_1; 1.
DR PROSITE; PS51475; PROTEASOME_ALPHA_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000256|PROSITE-
KW ProRule:PRU00808}; Reference proteome {ECO:0000313|Proteomes:UP000274504};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 332..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..28
FT /note="Proteasome alpha-type subunits"
FT /evidence="ECO:0000259|PROSITE:PS00388"
SQ SEQUENCE 588 AA; 67610 MW; FEFEFA9C5AE0C0CB CRC64;
MFRNQYDHDV SVWSPQGRIH QIEYAMEAVK QGSAAVALKN KDFCVIVALK RAPSELSSYQ
EKLIPIDSHI GMAITGLTAD GFLLARHMRR ECADNRWAYS EPLPVSRLLN KISLKMQIPT
QQYGRRPFGV GMLITGYDEQ GPHVYYLCPS SNAYDCKCFA VGSRSQSART YLERHLDKFS
DCSLDELIVH GVKALKGCLP VEVELSGKNC ALAIVGKNKN FTVCPEEEVE PYLTQATEAQ
SLETDDSYSS SSQLLNWLLT ADELNSRRQD CNVSTRKRLA EQFRAKVEAL GRMEVEPSFL
TAEEELIIVK RNIFAMYGFY QQFDDPQLPA DASFFIILFT FVFGFAATYL KRFYLNNSVM
DYSPREMMLT SLYLAFKAAD YPISLNRFVD HIPRNRERYH AFISRSELFL MDKLLYDLWI
HPPYRPLVGF LVELITYRRG IDPSMTDEEA TDLMNSLRKE GYEIINTWFQ TDLCFTNPPS
QYALAVVMEL GRRYPELQAE DFVNNVVLGN VTAEVGDEES VEQKKERLWE RLEAIQTMIS
EFDFIVDLSV GLELENVLAE CRNPLYDIDS DEYKEIQKQA MERMSFLD
//
