ID A0A0R3WJ93_HYDTA Unreviewed; 909 AA.
AC A0A0R3WJ93;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Peripheral plasma membrane protein CASK {ECO:0000313|WBParaSite:TTAC_0000072901-mRNA-1};
GN ORFNames=TTAC_LOCUS730 {ECO:0000313|EMBL:VDM16905.1};
OS Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Hydatigera.
OX NCBI_TaxID=6205 {ECO:0000313|Proteomes:UP000046396, ECO:0000313|WBParaSite:TTAC_0000072901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TTAC_0000072901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM16905.1, ECO:0000313|Proteomes:UP000274429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MAGUK family.
CC {ECO:0000256|ARBA:ARBA00007014}.
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DR EMBL; UYWX01000085; VDM16905.1; -; Genomic_DNA.
DR STRING; 6205.A0A0R3WJ93; -.
DR WBParaSite; TTAC_0000072901-mRNA-1; TTAC_0000072901-mRNA-1; TTAC_0000072901.
DR Proteomes; UP000046396; Unplaced.
DR Proteomes; UP000274429; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR CDD; cd00071; GMPK; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd12035; SH3_MPP1-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 6.10.140.620; -; 1.
DR Gene3D; 1.10.287.650; L27 domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR014775; L27_C.
DR InterPro; IPR004172; L27_dom.
DR InterPro; IPR036892; L27_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR PANTHER; PTHR23122:SF7; PERIPHERAL PLASMA MEMBRANE PROTEIN CASK; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF02828; L27; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00569; L27; 2.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00220; S_TKc; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF101288; L27 domain; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS51022; L27; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000274429};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 12..277
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 395..451
FT /note="L27"
FT /evidence="ECO:0000259|PROSITE:PS51022"
FT DOMAIN 493..574
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 580..651
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 717..894
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT REGION 459..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 909 AA; 102691 MW; C82DB7A79E26A007 CRC64;
MGDEDVLFDD TYQLCEIIGK GPFSVVRRCV HHESGQSFAV KIIDITKFTG SPGLSTADLK
REASICHLLK HPHIVELIET YSSDGMLYMV FEYMEGADLC HEIVKRATAG FIYSEAVASH
YMRQVLEAIK YCHENNVVHR DLKPHCVVLA NKQNSAPAKI GGFGIADQLN PDIDCFPDGR
IGTPHYMSPE MLRHEPYGKP VDAWSCGVLL SVLLGGSLPF YGTRETLYSQ ILNGQYRMNS
DVWDAVSSEA KDLAVKLLDV DPNRRMTIEE ALRHPWIAQK SRAPKTHLHA TVEALKHFNA
RRRLKNAILA AVSSTKWASF HIDADGLEAA EDDEVTSAAV SLILDSLEEM QCLTEAGSEA
MKWKELAFQD QQLCDLLELY DLINSNPLSP NVTLPDNATV KAQDVIDELT GTVSEDFVHD
ADELRYILTL PHFRALLRAR DVIAHDVYGE AAIRVTPPPT SAFGTSTTNS DEGGKDDADC
PADSGHHITR VRLVQFQKTT DEPMGITLKL NEEDKCIVAR IMHGGMIHRQ GTLHVGDELR
EINAEPVLGK SVEYLQRRLR EARGSVTLKI VPSYRTNPIQ CEIYVRAMFN YNPEADELIP
CTQAGIRFHV GDILQIISKD DHNWWQARLW GSDPQSPAGL IPSPEFQEWR AANRAAEYSH
GHGNQQVVNC GSWFMKKKRG NHGSGRSSSE RTRYSVMYDQ LDLYTYEEVV RLPTFRRRTL
VLLGAHGVGR RHIKNCLIQS APDKYAYPIP HTTRAPRKDE VYGKNYYFVT QEEMMRDITN
NEYLEYGTHE QAMYGTKLDT IRQIHAAGLI AILDVEPQAL KVLRTAEFAP CVIFIAAPDL
NTIFSDLNCP NDGSLERLAR ESQLLEQHFE HFFDMKIVNN DMEETIKKLH CGIEEFQTRP
QWIPVTWIY
//
