ID A0A0R3WL16_HYDTA Unreviewed; 277 AA.
AC A0A0R3WL16;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Neur_chan_LBD domain-containing protein {ECO:0000313|WBParaSite:TTAC_0000144901-mRNA-1};
GN ORFNames=TTAC_LOCUS1436 {ECO:0000313|EMBL:VDM17991.1};
OS Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Hydatigera.
OX NCBI_TaxID=6205 {ECO:0000313|Proteomes:UP000046396, ECO:0000313|WBParaSite:TTAC_0000144901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TTAC_0000144901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM17991.1, ECO:0000313|Proteomes:UP000274429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
CC {ECO:0000256|RuleBase:RU000687}.
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DR EMBL; UYWX01000313; VDM17991.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0R3WL16; -.
DR STRING; 6205.A0A0R3WL16; -.
DR WBParaSite; TTAC_0000144901-mRNA-1; TTAC_0000144901-mRNA-1; TTAC_0000144901.
DR Proteomes; UP000046396; Unplaced.
DR Proteomes; UP000274429; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR CDD; cd18987; LGIC_ECD_anion; 1.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR InterPro; IPR018000; Neurotransmitter_ion_chnl_CS.
DR PANTHER; PTHR18945:SF898; GLUTAMATE-GATED CHLORIDE CHANNEL; 1.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR PRINTS; PR00252; NRIONCHANNEL.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
DR PROSITE; PS00236; NEUROTR_ION_CHANNEL; 1.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU000687};
KW Ion transport {ECO:0000256|RuleBase:RU000687};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000274429};
KW Signal {ECO:0000256|RuleBase:RU000687};
KW Transport {ECO:0000256|RuleBase:RU000687}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|RuleBase:RU000687"
FT CHAIN 18..277
FT /evidence="ECO:0000256|RuleBase:RU000687"
FT /id="PRO_5035330352"
FT DOMAIN 34..261
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
SQ SEQUENCE 277 AA; 31769 MW; 1F373D2F9D4A60E0 CRC64;
MLLHLLLSVL ATAPALASYC LEGATGDNCD DLDAIINKLF TNYSRYERPK PHHCDADNTT
SDTVFVEINF YIKSLSAVNI VDMDFRLDTL LRQRWYDPRL DVGTLYNYSD VPIHLHMLDI
WLPDLFFRNS KSSTLHAITT PNTLAWINSN GMITYSQKLT IELSCPMQLW DFPMDTQHCS
ANIGSYGYST RDLEFRWWNE GGYDCSGQKR SGSVLNAAVQ LEDNQINEYT VVKHTCTYCD
RAYKTTGKFS CLNVEFELSR KFGFYLIYAY LPSLLVV
//
