ID A0A0R3X3M0_HYDTA Unreviewed; 990 AA.
AC A0A0R3X3M0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Rho-GAP domain-containing protein {ECO:0000313|WBParaSite:TTAC_0000795301-mRNA-1};
GN ORFNames=TTAC_LOCUS7938 {ECO:0000313|EMBL:VDM32414.1};
OS Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Cyclophyllidea; Taeniidae; Hydatigera.
OX NCBI_TaxID=6205 {ECO:0000313|Proteomes:UP000046396, ECO:0000313|WBParaSite:TTAC_0000795301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TTAC_0000795301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDM32414.1, ECO:0000313|Proteomes:UP000274429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYWX01020423; VDM32414.1; -; Genomic_DNA.
DR STRING; 6205.A0A0R3X3M0; -.
DR WBParaSite; TTAC_0000795301-mRNA-1; TTAC_0000795301-mRNA-1; TTAC_0000795301.
DR Proteomes; UP000046396; Unplaced.
DR Proteomes; UP000274429; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR037769; Abr/Bcr.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23182; BREAKPOINT CLUSTER REGION PROTEIN BCR; 1.
DR PANTHER; PTHR23182:SF1; RHO GTPASE ACTIVATING PROTEIN AT 1A, ISOFORM E; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00239; C2; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000274429}.
FT DOMAIN 605..721
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 750..962
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 107..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..954
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 436..474
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..72
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 990 AA; 113029 MW; 9FE18C25BCA4C874 CRC64;
MPKHIDKEVK RALADKTSDL GPLDDESSSD DSVSLENYLD EYDENKKSVS SEFRPELANV
KNKDSDDGVK LRHRVEVPLD TRTKGFNRES RKRKTLDEYL CKGSIESEQE GKQAKGSTRV
KSTPQTPLDS NSIYTSLKTQ ADDKAKDLPK QVSTKKTMEA RFKGMLEDEF QNSRDLAELL
QVKLRMYTGS LLHTLQERAS IQNSFGKHFC TDIFALLKEI YGMQIGVVPH LKNICDKQQP
NIEDLLSKLC ERQKLLSKYA QLVLPRLTKL QSKSASIFTS NARAVFLMHN PCDISLQRLK
EYVQPDDSNY EIITVAQEEL LDISSDLAPV RQVKEPIKYS VLVEMRNPPN GERKLMSIFL
FDNVLVCARQ RVIVLRKHFT QDSDSETASV STSAKDQSDL IMNARTISRY EVKWFIPLEQ
LESLDSKGIA FDEENLLERL QKIETLKRKI VKIRQELQEE TSKLDKESKR QKLKIPKIHR
LRSYLYSLQA DLVLQTPKLP LFISAADDQK YCLLMASEKE RITWESAIMH AKADCKLRSR
RQSPASVSKR NSLLRPFSTT IRESRRAAHV RRSSTESEIS PQDEILKNEL SYMINHCKTA
VPLNKLGKVI ISGNALSGIL EVCVHEISGL TEPGPYYVAI EVDFYGLFEL VAKTKSINDT
TNPRWDQTFM FEIETSQTIC FTVFRQSIVF GQVELPLEED QLDQKKVSHH LNTDEKVSKP
VYLQISILYN ERKKQNVRPR SKKQSDVFGQ PLDEVLKRDQ ADRERLKKQI GGNKNYEELR
VPVLVTACVE EIERRGLQEE GIYRVSGSVT TVARLQDLFD RDTSLAVKQI GDYDIHVISS
LLKLFFRELP EPLIPTNSFN DLVKASAHSD EKKKLGEFSR ILRKMPRVNL DTLQYLMDHL
IRVCQYESEN KMNIGNLSLI WTMTLFQPEN VPTTPKASSA TAETPDAKKA PSQSLQSAAS
VGVLQTMILS TIFDAYANGK LDLPTHKSTF
//
