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Database: UniProt
Entry: A0A0R4IRY0_DANRE
LinkDB: A0A0R4IRY0_DANRE
Original site: A0A0R4IRY0_DANRE 
ID   A0A0R4IRY0_DANRE        Unreviewed;       401 AA.
AC   A0A0R4IRY0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 2.
DT   18-JUL-2018, entry version 19.
DE   SubName: Full=BAI1-associated protein 2b {ECO:0000313|Ensembl:ENSDARP00000138148};
GN   Name=baiap2b {ECO:0000313|Ensembl:ENSDARP00000138148,
GN   ECO:0000313|ZFIN:ZDB-GENE-100812-7};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000138148, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|Ensembl:ENSDARP00000138148, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000138148,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000138148}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000138148};
RG   Ensembl;
RL   Submitted (NOV-2015) to UniProtKB.
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DR   EMBL; BX255898; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSDART00000169889; ENSDARP00000138148; ENSDARG00000103333.
DR   ZFIN; ZDB-GENE-100812-7; baiap2b.
DR   GeneTree; ENSGT00390000005995; -.
DR   Reactome; R-DRE-2029482; Regulation of actin dynamics for phagocytic cup formation.
DR   Reactome; R-DRE-4420097; VEGFA-VEGFR2 Pathway.
DR   Reactome; R-DRE-5663213; RHO GTPases Activate WASPs and WAVEs.
DR   Proteomes; UP000000437; Chromosome 12.
DR   ExpressionAtlas; A0A0R4IRY0; baseline.
DR   GO; GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR   GO; GO:0032956; P:regulation of actin cytoskeleton organization; IEA:InterPro.
DR   CDD; cd11915; SH3_Irsp53; 1.
DR   Gene3D; 1.20.1270.60; -; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR013606; I-BAR_dom.
DR   InterPro; IPR030128; IRSp53.
DR   InterPro; IPR027681; IRSp53/IRTKS/Pinkbar.
DR   InterPro; IPR035594; Irsp53_SH3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR14206; PTHR14206; 1.
DR   PANTHER; PTHR14206:SF3; PTHR14206:SF3; 1.
DR   Pfam; PF08397; IMD; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF103657; SSF103657; 1.
DR   SUPFAM; SSF50044; SSF50044; 1.
DR   PROSITE; PS51338; IMD; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW   SH3 domain {ECO:0000256|PROSITE-ProRule:PRU00192,
KW   ECO:0000256|SAAS:SAAS00989295}.
FT   DOMAIN        1    126       IMD. {ECO:0000259|PROSITE:PS51338}.
FT   DOMAIN      254    317       SH3. {ECO:0000259|PROSITE:PS50002}.
FT   COILED        3     23       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   401 AA;  44728 MW;  0EA0BB5D3C763E73 CRC64;
     MEHKSKGESL EKCQAELKKL RRKSQGSKNP SKYGDKEMQY VETISSKQNE LDNYISESYK
     NALSEERRRY CFLVDRQCAV AKTSNTYHTK GRDLLTQKIP LWQQACADPN KLPERAMLLA
     QQMSSGAAGT LGPSVHHTSK SNLTISDPIP GAKPLPVPPE LAALMGNQQS RMMGADSVPI
     VNGSGVHVGE DYQRWMETRA AHDKQSQQPH RHGGESFSNT LPVRKVAPVK PKNTLAETQT
     LPRSSSMTTG LERNGRTRVQ ALFSHAAGDN STLLSFTEGD IITLLVPEAR DGWHYGENEK
     NRMRGWFPFS YTRLIAEPDS NKLHVSLQHN RSSSTGNLLE REMALPTPDY GMPTRFAQQQ
     STAHSRQRPY SVAVPGFSQQ GLEEYESRFQ ASTEGKLIST V
//
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