ID A0A0S1SME1_9BACT Unreviewed; 549 AA.
AC A0A0S1SME1; A0A0S1SHC7; A0A0S1SLS0; A0A0S1ST71; A0A0S1SXA7;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=2-isopropylmalate synthase {ECO:0000313|EMBL:ALM12896.1};
GN ORFNames=PeribacterD1_0195 {ECO:0000313|EMBL:ALM12896.1};
OS Candidatus Peribacter riflensis.
OC Bacteria; Candidatus Peregrinibacteria; Candidatus Peribacteria;
OC Candidatus Peribacterales; Candidatus Peribacteraceae; Peribacter.
OX NCBI_TaxID=1735162 {ECO:0000313|EMBL:ALM12896.1, ECO:0000313|Proteomes:UP000069135};
RN [1] {ECO:0000313|Proteomes:UP000069135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Anantharaman K., Brown C.T., Burstein D., Castelle C.J., Probst A.J.,
RA Thomas B.C., Williams K.H., Banfield J.F.;
RT "Analysis of five complete genome sequences for members of the class
RT Peribacteria in the recently recognized Peregrinibacteria bacterial
RT phylum.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ALM12896.1, ECO:0000313|Proteomes:UP000069135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIFOXYD1_FULL_PER-ii_59_16 {ECO:0000313|EMBL:ALM12896.1};
RX PubMed=26844018;
RA Anantharaman K., Brown C.T., Burstein D., Castelle C.J., Probst A.J.,
RA Thomas B.C., Williams K.H., Banfield J.F.;
RT "Analysis of five complete genome sequences for members of the class
RT Peribacteria in the recently recognized Peregrinibacteria bacterial
RT phylum.";
RL PeerJ 4:E1607-E1607(2016).
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DR EMBL; CP013065; ALM12896.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0S1SME1; -.
DR STRING; 1735162.PeribacterB2_0195; -.
DR KEGG; prf:PeribacterA2_0195; -.
DR Proteomes; UP000069135; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009082; P:branched-chain amino acid biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.160.270; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR036230; LeuA_allosteric_dom_sf.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR10277:SF9; 2-ISOPROPYLMALATE SYNTHASE 1, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR10277; HOMOCITRATE SYNTHASE-RELATED; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF110921; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 14..278
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 549 AA; 60113 MW; 26710420B86E070B CRC64;
MESASSPITE PQQVIVFDTT LRDGDQAGVL FDEDQKVVIA HSLEDIGVDV IEAGNAFSGT
FDQRSIARIA QEVRRPVICS LAICKRESVE ASAKALERAE HPRIHIYRAS SREHLDKVFH
GMGEEQYLDD IAAHIELARR YVPDVEYSAE DATNTPREFL ARIGIRAAEA GATTFNIPDT
YGQALPTEME ELMAYLSQNI PAIREHRMRQ STHNHDDHGL ATANTLYALK GMGDALKQAE
LTVNGLGERA GNASLAETVM TARYRKDRFP MVNFDHIRAE MLVRLSRIVS ALSRVSVPRN
TPFVGTGINA LGTGTHVAAQ DRIGIRNGAY RDNVPQDVGF DDFNIEFGAT SGKGVADVYA
RQLGYHIPET DLVPFTAFAK AFAETKRGTE CRIVTPDEYR SLLFQYFGVG VPIESTGGTQ
FLRAAKNGQW EVHLTVSGRN GEQTLTGHSE EKQGVLQAVT AILREQSGLD FQLIDQWEES
DQTQGERSGS VTGVTIRIGK MECQGTAQGT DVTETTVRAL FDAVNKAKLA SLLTEQQSAT
SVGAPGRVK
//
